Latest submissions
Now showing items 101-120 of 149
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Nanosized liposomes containing bile salt: A vesicular nanocarrier for enhancing oral bioavailability of BCS class III drug
(Canadian Society for Pharmaceutical Sciences, 2017)PURPOSE: Liposomes have been studied as a colloidal carrier in drug delivery systems, especially for oral administration. However, their low structural integrity in the gut is still a major shortcoming. Membrane disruptive ... -
Luteolin, a flavonoid, as an anticancer agent: A review
(Elsevier Masson SAS., 2019)Many food-derived phytochemicals and their derivatives represent a cornucopia of new anti-cancer compounds. Luteolin (3,4,5,7-tetrahydroxy flavone) is a flavonoid found in different plants such as vegetables, medicinal ... -
A sedge plant as the source of Kangaroo Island propolis rich in prenylated p-coumarate ester and stilbenes
(Elsevier Ltd., 2016)Propolis samples from Kangaroo Island, South Australia, were investigated for chemical constituents using high-field nuclear magnetic resonance spectral profiling. A type of propolis was found containing a high proportion ... -
Computer-aided discovery of antimicrobial agents as potential enoyl acyl carrier protein reductase inhibitors
(University of Benin, 2017)Purpose: To perform a virtual screening for a set of drug-like ligand library against the Staphylococcus aureus enoyl acyl carrier protein reductase, saFabI. Methods: The virtual screening was conducted based on a previously ... -
Herbal medicines: A cross-sectional study to evaluate the prevalence and predictors of use among Jordanian adults
(BioMed Central Ltd., 2020)Introduction: Understanding why adults resort to herbal medicine can help in planning interventions aimed at increasing awareness regarding herbal use. This study sought to investigate the prevalence and to determine factors ... -
Butylglyceryl pectin nanoparticles: Synthesis, formulation and characterization
(MDPI AG., 2019)Pectin is a polysaccharide with very good gel forming properties that traditionally has found important applications in foods and pharmaceutical industries. Although less studied, chemical modifications of pectin leading ... -
Quality attributes and in vitro bioequivalence of different brands of amoxicillin trihydrate tablets
(MDPI AG., 2017)Bacterial resistance and antibiotic drug effectiveness can be related to administering generic products with a subtherapeutic dose or poor in vivo drug release. The aim of this study was to investigate whether locally ... -
Transdermal patches: Design and current approaches to painless drug delivery
(Sciendo, 2019)Use of transdermal patches can evade many issues associated with oral drug delivery, such as first-pass hepatic metabolism, enzymatic digestion attack, drug hydrolysis and degradation in acidic media, drug fluctuations, ... -
Proanthocyanidins: A comprehensive review
(Elsevier Masson SAS., 2019)Proanthocyanidins are condensed tannins with various pharmacological properties. These phytochemicals are considered as ‘offense and defense molecules because of their human health benefits. The validation of their diverse ... -
Secondary metabolites profiling, biological activities and computational studies of Abutilon figarianum webb (Malvaceae)
(MDPI AG., 2020)This research endeavors to inspect the chemical and biological profiling of methanol anddichloromethane (DCM) extracts prepared fromAbutilon figarianumWebb. Total bioactive constituentsand secondary metabolites were ... -
Nonsteroidal Anti-inflammatory Drugs Utilization Patterns and Risk of Adverse Events due to Drug-Drug Interactions among Elderly Patients: A Study from Jordan
(Elsevier B.V., 2020)Background: Worldwide, the prescribing pattern of the Nonsteroidal Anti-inflammatory Drugs (NSAIDs) has increased. They are considered highly effective medications in controlling various conditions including inflammatory ... -
Nurses perception of pharmaceutical care practice: A qualitative approach
(University of Benin, 2020)Purpose: To evaluate the perception of nurses regarding pharmaceutical care services in the healthcare system of Khyber Pakhtunkhwa (KPK) Province of Pakistan. Methods: This qualitative study was implemented by conducting ... -
A cross-sectional study on knowledge, attitude and practices of medical doctors towards antibiotic prescribing patterns and resistance in Khyber Pakhtun Khawah, Pakistan
(Open Science Publishers LLP Inc., 2017)Irrational prescribing and resistance to antibiotics are major health concerns globally. The aim of this study was to assess the physicians' knowledge, attitude and practice about antibiotic prescribing and resistance in ... -
Spasmolytic and antimicrobial activities of crude extract of bongardia chrysogonum l. Tubers
(Asian Network for Scientific Information, 2017)Background and Objective: Although Bongardia chrysogonum L. (family Berberidaceae) has been used in many countries in traditional medicine to treat gastrointestinal tract disorders, scientific evidence for this treatment ... -
Sedative, muscle relaxant-like effects, and molecular docking study of compounds isolated from salvia leriifolia
(Springer Science and Business Media Deutschland GmbH, 2020)Salvia leriifolia Benth., Lamiaceae, an endemic medicinal plant of the northern region of Iran, has been documented as sedative. It has been used in traditional medicine for its muscle relaxation effect. The need for ... -
Safety Assessment of Neoadjuvant Pertuzumab Combined with Trastuzumab in Nonmetastatic HER2-Positive Breast Cancer in Postmenopausal Elderly Women of South Asia
(Hindawi Limited, 2018)Aim: To evaluate the safety issues and adverse effects of using TCHP regimen (docetaxel, carboplatin, trastuzumab, and pertuzumab) versus TCP regimen (docetaxel, carboplatin, and trastuzumab) in older postmenopausal women ... -
Assessment of extrapyramidal symptoms associated with psychotropics pharmacological treatments, and associated risk factors
(Bentham Science Publishers, 2021)Background: Extrapyramidal Symptoms (EPS) are unwanted symptoms commonly originating from the use of certain medications. The symptoms can range from minimal discomfort to permanent involuntary muscular movements. The aims ... -
The evolving role of community pharmacists during COVID-19 in the UAE; assessing preparedness and knowledge
(Oxford University Press, 2021)Objectives To investigate community pharmacists' knowledge about COVID-19 and their preparedness for the pandemic. Methods This cross-sectional online survey was conducted (in community pharmacies in the United Arab Emirates) ... -
A quantitative evaluation of evidence-based beliefs and implementation among community pharmacists: Findings and impact from United Arab Emirates
(Dove Medical Press Ltd., 2021)Background: The flux of pharmaceutical data can have a negative impact on the complexity of a pharmacist’s decision-making process, which will demand an extensive evaluation from healthcare providers trying to choose the ... -
Kinetics of oxidation of atropine by K2Cr2O7 in acidic aqueous solutions
(Chemical Publishing Co., 2018)Oxidation of atropine (ATN) by K2Cr2O7 has been studied kinetically in aqueous strongly acidic solutions. The kinetics of this reaction was investigated at different temperatures. A constant pH and constant ionic strength ...