Browsing Pharmaceutical Sciences by Title
Now showing items 121-140 of 146
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Quality attributes and in vitro bioequivalence of different brands of amoxicillin trihydrate tablets
(MDPI AG., 2017)Bacterial resistance and antibiotic drug effectiveness can be related to administering generic products with a subtherapeutic dose or poor in vivo drug release. The aim of this study was to investigate whether locally ... -
A quantitative evaluation of evidence-based beliefs and implementation among community pharmacists: Findings and impact from United Arab Emirates
(Dove Medical Press Ltd., 2021)Background: The flux of pharmaceutical data can have a negative impact on the complexity of a pharmacist’s decision-making process, which will demand an extensive evaluation from healthcare providers trying to choose the ... -
Recent advances in the development of sialyltransferase inhibitors to control cancer metastasis: A comprehensive review
(Elsevier Masson s.r.l., 2023)Metastasis accounts for the majority of cancer-associated mortalities, representing a huge health and economic burden. One of the mechanisms that enables metastasis is hypersialylation, characterized by an overabundance ... -
Recent applications of quantitative analytical FTIR spectroscopy in pharmaceutical, biomedical, and clinical fields: A brief review
(Walter de Gruyter GmbH, 2022)Qualitative Fourier transform infrared (FTIR) spectroscopy has long been established and implemented in a wide variety of fields including pharmaceutical, biomedical, and clinical fields. While the quantitative applications ... -
Safety Assessment of Neoadjuvant Pertuzumab Combined with Trastuzumab in Nonmetastatic HER2-Positive Breast Cancer in Postmenopausal Elderly Women of South Asia
(Hindawi Limited, 2018)Aim: To evaluate the safety issues and adverse effects of using TCHP regimen (docetaxel, carboplatin, trastuzumab, and pertuzumab) versus TCP regimen (docetaxel, carboplatin, and trastuzumab) in older postmenopausal women ... -
Scale validation for the identification of falsified hand sanitizer: public and regulatory authorities perspectives from United Arab Emirates
(BioMed Central Ltd, 2020)Background: Since the time of declaration of global pandemic of COVID-19 by World Health Organization (WHO), falsified hand sanitizers surfaced regularly in markets, posing possible harm to public due to unlisted inclusion ... -
Scrophularia peyronii Post. from Jordan: Chemical Composition of Essential Oil and Phytochemical Profiling of Crude Extracts and Their In Vitro Antioxidant Activity
(MDPI, 2023)The genus Scrophularia is one of the largest genera belonging to the Scrophulariaceae family. Different members of the genus exhibit an interesting, wide spectrum of bioactivities. Accordingly, the current study aimed to ... -
Secondary metabolites profiling, biological activities and computational studies of Abutilon figarianum webb (Malvaceae)
(MDPI AG., 2020)This research endeavors to inspect the chemical and biological profiling of methanol anddichloromethane (DCM) extracts prepared fromAbutilon figarianumWebb. Total bioactive constituentsand secondary metabolites were ... -
Sedative, muscle relaxant-like effects, and molecular docking study of compounds isolated from salvia leriifolia
(Springer Science and Business Media Deutschland GmbH, 2020)Salvia leriifolia Benth., Lamiaceae, an endemic medicinal plant of the northern region of Iran, has been documented as sedative. It has been used in traditional medicine for its muscle relaxation effect. The need for ... -
A sedge plant as the source of Kangaroo Island propolis rich in prenylated p-coumarate ester and stilbenes
(Elsevier Ltd., 2016)Propolis samples from Kangaroo Island, South Australia, were investigated for chemical constituents using high-field nuclear magnetic resonance spectral profiling. A type of propolis was found containing a high proportion ... -
Spasmolytic and antimicrobial activities of crude extract of bongardia chrysogonum l. Tubers
(Asian Network for Scientific Information, 2017)Background and Objective: Although Bongardia chrysogonum L. (family Berberidaceae) has been used in many countries in traditional medicine to treat gastrointestinal tract disorders, scientific evidence for this treatment ... -
Stress-driven discovery in the natural products: A gateway towards new drugs
(Elsevier Masson SAS., 2019)Elicitation by chemical means including heavy metals is one of a novel technique for drug discoveries. In this review, the effect of heavy metals on animal, plants and microorganisms for the production of novel compounds ... -
Structure–Activity Relationship of Benzofuran Derivatives with Potential Anticancer Activity
(MDPI, 2022)Benzofuran is a heterocyclic compound found naturally in plants and it can also be obtained through synthetic reactions. Multiple physicochemical characteristics and versatile features distinguish benzofuran, and its ... -
Survey data for COVID-19 vaccine preference analysis in the United Arab Emirates
(Elsevier Inc., 2020)In response to the call for interdisciplinary research on the potential effects of the coronavirus pandemic [1], this article presents a novel data set on individuals’ COVID-19 vaccine preferences in the United Arab Emirates ... -
Synthesis and calcium channel blocking activity of 1, 4-dihydropyridine derivatives containing ester substitute and phenyl carbamoyl group
(Science Publications, 2011)Problem statement: Several studies on the synthesis of new nifedipine analogs have been carried out, but the literature reveled that no study on the synthesis and calcium channel blocking activity of the substituted ester ... -
Synthesis and Characterization of Carboxymethyl Chitosan Nanosponges with Cyclodextrin Blends for Drug Solubility Improvement
(MDPI, 2022)This study aimed to enhance the solubility and release characteristics of docetaxel by synthesizing highly porous and stimuli responsive nanosponges, a nano-version of hydrogels with the additional qualities of both hydrogels ... -
Synthesis and Evaluation of Finasteride-Loaded HPMC-Based Nanogels for Transdermal Delivery: A Versatile Nanoscopic Platform
(NLM (Medline), 2022)Herein, we report nanogels comprising diverse feed ratio of polymer hydroxypropyl methylcellulose (HPMC), monomer acrylic acid (AA), and cross-linker methylene bisacrylamide (MBA) fabricated for transdermal delivery of ... -
Synthesis, characterization, and antimicrobial evaluation of oxadiazole congeners
(MDPI AG., 2011)A series of 1,3-oxazole, 1,3-thiazole, isomeric 1,2,4-oxadiazole, 1,3,4-oxadiazole, and 1,2,3,4-tetrazole heterocycles was synthesized. All the compounds shared as a common feature the presence of a 4-hydroxyphenyl ... -
Synthesis, kinetic studies and in-silico investigations of novel quinolinyl-iminothiazolines as alkaline phosphatase inhibitors
(NLM (Medline), 2023)Deposition of hydroxyapatite (HA) or alkaline phosphate crystals on soft tissues causes the pathological calcification diseases comprising of end-stage osteoarthritis (OA), ankylosing spondylitis (AS), medial artery ... -
Synthesis, molecular docking and ADMET studies of bis-benzimidazole-based thiadiazole derivatives as potent inhibitors, in vitro α-amylase and α-glucosidase
(Elsevier B.V., 2023)Different research synthetic methods have been developed recently for the synthesis of bis-benzimidazole analogs to investigate various biological significances. In this present study, an attempt was made to synthesize a ...