Browsing Pharmaceutical Sciences by Title
Now showing items 106-125 of 146
-
Online medication purchasing during the Covid-19 pandemic: A pilot study from the United Arab Emirates
(Springer, 2021)Abstract Background: Since the WHO announced that Covid-19 had become a global pandemic, online pharmacies have emerged as an extremely popular way to purchase medication due to the quarantine measures introduced by ... -
Papain-Decorated Mucopenetrating SEDDS: A Tentative Approach to Combat Absorption Issues of Acyclovir via the Oral Route
(MDPI, 2022)The aim of the current study was to enhance the oral bioavailability of Acyclovir (ACV) based on the papain-functionalized self-emulsifying drug delivery systems (SEDDS). The optimum control SEDDS formulation comprised of ... -
The patterns of herbal medicine use in the United Arab Emirates; A national study
(Grupo de Investigacion en Atencion Farmaceutica, 2022)Objectives: To examine the pattern, nature, and attitude towards herbal medicines usage in the UAE. Methods: A cross-sectional national questionnaire was distributed over five weeks in 7 emirates of UAE: The questioner was ... -
Paving Luteolin Therapeutic Potentialities and Agro-Food-Pharma Applications: Emphasis on in Vivo Pharmacological Effects and Bioavailability Traits
(Hindawi Limited, 2021)Luteolin is a naturally occurring secondary metabolite belonging to the class of flavones. As many other natural flavonoids, it is often found in combination with glycosides in many fruits, vegetables, and plants, contributing ... -
Pharmacokinetic interaction of rosuvastatin with artichoke (Cynara scolymusL.) leaf extract in rats
(Open Science Publishers LLP Inc., 2023)Dyslipidemia is a prevalent disease among the international population that has substantially increased, which can be treated with several hypolipidemic drugs such as rosuvastatin. Artichoke is a plant that is commonly ... -
The pharmacological basis of Cuscuta reflexa whole plant as an antiemetic agent in pigeons
(Elsevier Inc., 2020)Cuscuta reflexa has been traditionally used as an antiemetic. Additionally, it has been used in various herbal formulations for the treatment of emesis. So far, there is no scientific evidence of the plant extract as ... -
Pharmacological Validation for the Folklore Use of Ipomoea nil against Asthma: In Vivo and In Vitro Evaluation
(NLM (Medline), 2022)Oxidative stress is the key factor that strengthens free radical generation which stimulates lung inflammation. The aim was to explore antioxidant, bronchodilatory along with anti-asthmatic potential of folkloric plants ... -
Phytochemical profiling, antioxidant and antiproliferation potential of Euphorbia milii var.: Experimental analysis and in-silico validation
(Elsevier B.V., 2020)This study was aimed to investigate the anticancer potential of Euphorbia milii (E. milii) using an exquisite combination of phytopharmacological and advanced computational techniques. The chloroform fraction (Em-C) of E. ... -
Polyvinylpyrrolidone K-30-Based Crosslinked Fast Swelling Nanogels: An Impeccable Approach for Drug's Solubility Improvement
(NLM (Medline), 2022)Poor solubility is a global issue of copious pharmaceutical industries as large number of drugs in development stage as well as already marketed products are poorly soluble which results in low dissolution and ultimately ... -
Potential strategies for combating COVID-19
(Springer, 2020)Coronavirus disease 2019, also known as COVID-19, is caused by a novel coronavirus named severe acute respiratory syndrome coronavirus 2, or SARS-CoV-2. The infection has now catapulted into a full-blown pandemic across ... -
Prediction of lisinopril pediatric dose from the reference adult dose by employing a physiologically based pharmacokinetic model
(BioMed Central, 2020)Background: This study aimed to assess the pediatric lisinopril doses using an adult physiological based pharmacokinetic (PBPK) model. As the empirical rules of dose calculation cannot calculate gender-specific pediatric ... -
Preliminary Investigation of Linum usitatissimum Mucilage-Based Hydrogel as Possible Substitute to Synthetic Polymer-Based Hydrogels for Sustained Release Oral Drug Delivery
(MDPI, 2022)The aim of this study was to investigate the potential of Linum usitatissimum mucilage, a natural polymer, in developing a sustained release hydrogel for orally delivered drugs that require fre-quent dosing. For this ... -
Preparation and Characterization of Theophylline Controlled Release Matrix System Incorporating Poloxamer 407, Stearyl Alcohol, and Hydroxypropyl Methylcellulose: A Novel Formulation and Development Study
(Multidisciplinary Digital Publishing Institute (MDPI), 2024-03)Background: Theophylline (THN), a bronchodilator with potential applications in emerging conditions like COVID-19, requires a controlled-release delivery system due to its narrow therapeutic range and short half-life. This ... -
Proanthocyanidins: A comprehensive review
(Elsevier Masson SAS., 2019)Proanthocyanidins are condensed tannins with various pharmacological properties. These phytochemicals are considered as ‘offense and defense molecules because of their human health benefits. The validation of their diverse ... -
Protocol for systematic review and meta-analysis of randomized controlled trials, cost-benefit analysis and interrupted time-series interventions on pharmacist’s prescribing
(Grupo de Investigacion en Atencion Farmaceutica, 2022)Background: Shortening the process of prescribing via permitting the pharmacist to select the most appropriate pharmaceuticals for each particular patient may provide great opportunities for pharmacists to develop suitable ... -
Quality attributes and in vitro bioequivalence of different brands of amoxicillin trihydrate tablets
(MDPI AG., 2017)Bacterial resistance and antibiotic drug effectiveness can be related to administering generic products with a subtherapeutic dose or poor in vivo drug release. The aim of this study was to investigate whether locally ... -
A quantitative evaluation of evidence-based beliefs and implementation among community pharmacists: Findings and impact from United Arab Emirates
(Dove Medical Press Ltd., 2021)Background: The flux of pharmaceutical data can have a negative impact on the complexity of a pharmacist’s decision-making process, which will demand an extensive evaluation from healthcare providers trying to choose the ... -
Recent advances in the development of sialyltransferase inhibitors to control cancer metastasis: A comprehensive review
(Elsevier Masson s.r.l., 2023)Metastasis accounts for the majority of cancer-associated mortalities, representing a huge health and economic burden. One of the mechanisms that enables metastasis is hypersialylation, characterized by an overabundance ... -
Recent applications of quantitative analytical FTIR spectroscopy in pharmaceutical, biomedical, and clinical fields: A brief review
(Walter de Gruyter GmbH, 2022)Qualitative Fourier transform infrared (FTIR) spectroscopy has long been established and implemented in a wide variety of fields including pharmaceutical, biomedical, and clinical fields. While the quantitative applications ... -
Safety Assessment of Neoadjuvant Pertuzumab Combined with Trastuzumab in Nonmetastatic HER2-Positive Breast Cancer in Postmenopausal Elderly Women of South Asia
(Hindawi Limited, 2018)Aim: To evaluate the safety issues and adverse effects of using TCHP regimen (docetaxel, carboplatin, trastuzumab, and pertuzumab) versus TCP regimen (docetaxel, carboplatin, and trastuzumab) in older postmenopausal women ...