Browsing Clinical Pharmacy by Title
Now showing items 1-20 of 107
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Activation of the GLP-1 receptor by chloropyrimidine derivatives
(Elsevier B.V., 2021)The anti-diabetic activities of a series of chloropyrimidine derviatives 2a-k and 4a-k were investigated after they were designed, synthesized, and docked against the GLP-1 receptor target. In comparison to exenatide, which ... -
Aducanumab Therapy to Treat Alzheimer's Disease: A Narrative Review
(Hindawi Limited, 2022)Background. Aducanumab, a new monoclonal antibody that targets β-amyloid aggregates, has been granted conditional approval by the U.S. FDA for treatment of mild Alzheimer's disease (AD). The approval of this drug without ... -
Amphiphilic Alkylated Pectin Hydrogels for Enhanced Topical Delivery of Fusidic Acid: Formulation and In Vitro Investigation
(MDPI, 2022)Hydrogels constructed of amphiphilically modified polysaccharides have attracted a lot of interest because of their potential to augment drug diffusion over the skin. This research describes the synthesis of amphiphilic ... -
Anti-convulsant effects of bongardia chrysogonum L. Tuber in the pentylenetetrazole-induced seizure model
(Asian Network for Scientific Information, 2017)Background and Objective: The dried tuber of Bongardia chrysogonum (L.) is a popular folk remedy for its use in the treatment of epilepsy in traditional medicine. The study aimed to evaluate the anti-oxidant and anti-convulsant ... -
Antibiotic Prescribing Patterns for Outpatient Pediatrics at a Private Hospital in Abu Dhabi: A Clinical Audit Study
(MDPI, 2022)Background: Antibiotics are commonly used in pediatrics. The aim and objectives were to evaluate the antibiotic prescribing patterns of pediatric outpatients at a private hospital in Abu Dhabi, UAE. Methods: A retrospective ... -
Antibiotic prescribing practices and errors among hospitalized pediatric patients suffering from acute respiratory tract infections: A multicenter, cross-sectional study in pakistan
(MDPI AG., 2019)Background and objective: The noncompliance of treatment guidelines by healthcare professionals, along with physiological variations, makes the pediatric population more prone to antibiotic prescribing errors. The present ... -
Appropriateness of antibiotic prescription among hospitalized patients with urinary tract infection in Jordan
(Open Science Publishers LLP Inc., 2023)Lack of adherence to recent antibiotic prescription guidelines leads to antibiotic resistance which causes treatment failure and the development of disease complications in patients with urinary tract infection (UTI). The ... -
Assessment of Knowledge, Attitude, and Practice of Physicians toward Pharmacovigilance in Public and Private Hospitals in Jordan
(University of Jordan,Deanship of Scientific Research, 2022)Knowledge, attitude, and practice toward pharmacovigilance (PV) among healthcare providers is strongly associated with the reporting of adverse drug reactions (ADRs). This study was conducted to evaluate knowledge, attitude, ... -
An Assessment of Quality of Life in Patients With Asthma Through Physical, Emotional, Social, and Occupational Aspects. A Cross-Sectional Study
(Frontiers Media S.A., 2022)Background: Asthma is a prevalent hyperactive airway disease with physical and emotional impact. Severe asthma is associated with considerable health-related quality of life (HRQoL). The aim of this study is to assess the ... -
Assessment of Therapeutic Effects of Platelet-Rich Plasma in Knee Osteoarthritis: Possible Role of Inflammatory Cytokines
(Science Publications, 2021)Osteoarthritis (OA) is a multifactorial disease that commonly affects the knee. Tumor Necrosis Factor-α (TNF-α) regulates inflammation during OA. Macrophage Migration Inhibitory Factor (MIF) may be involved in the ... -
Attitude and perception of pharmacists and healthcare professionals about the criteria used in drug formulary selection in the United Arab Emirates
(BioMed Central Ltd, 2022)Background: There is lack of both resources and expertise explains the limited extent to which pharmacoeconomic evidence is used in formulary decision-making. Objectives: The present study aims to assess attitude and ... -
Automated Detection of COVID-19 using Chest X-Ray Images and CT Scans through MultilayerSpatial Convolutional Neural Networks
(Universidad Internacional de la Rioja, 2021)The novel coronavirus-2019 (Covid-19), a contagious disease became a pandemic and has caused overwhelming effects on the human lives and world economy. The detection of the contagious disease is vital to avert further ... -
The availability, pricing, and affordability of essential diabetes medicines in 17 low-, middle-, and high-income countries
(Frontiers Media S.A., 2019)Background: One third of the world population does not have access to essential medicines. Diabetes require a long-term therapy, which incurs significant health care cost and thus impact access and affordability. This study ... -
Behavioral and neurochemical alterations induced by vanillin in a mouse model of Alzheimer's disease
(Asian Network for Scientific Information, 2017)Background and Objective: Alzheimer's disease (AD) is a progressive neurodegenerative disease where symptoms appear after significant neuronal loss. Current treatments for AD do not significantly alter the disease process, ... -
Blood pressure control and its associated factors in patients with hypertension and type 2 diabetes
(Modestum LTD, 2023)In this retrospective study, the medical records of hypertensive patients with type 2 diabetes attending two major hospitals were reviewed to find the factors associated with poor blood pressure control in patients who ... -
Breastfeeding friendly pharmacy from pharmacists perspective
(Modestum LTD, 2023)Objective: The primary goals of our research were to explore pharmacists’ perception of breastfeeding friendly pharmacy (BFPh) requirements and factors associated with their awareness about these requirements. Methods: A ... -
Cancerous lung nodule detection in CT-images
(Universitas Ahmad Dahlan, 2020)Diagnosis the computed tomography images (CT-images) is one of the images that may take a lot of time in diagnosis by the radiologist and may miss some of cancerous nodules in these images. Therefore, in this paper a new ... -
Cardiovascular health and the intestinal microbial ecosystem: The impact of cardiovascular therapies on the gut microbiota
(MDPI AG., 2021)It has become evident over the past several years that the intestinal microbial ecosystem plays a critical role in the development and prevention of cardiovascular diseases (CVDs) and other metabolic disorders, such as ... -
Causality and preventability assessment of adverse drug events of antibiotics among inpatients having different lengths of hospital stay: A multicenter, cross-sectional study in Lahore, Pakistan
(BioMed Central Ltd., 2018)Background: A large number of hospital admissions are attributed to adverse drug reactions (ADRs) and they are the fifth leading cause of death worldwide. The present study aimed to assess the causality and preventability ... -
Causality and preventability assessment of adverse drug reactions and adverse drug events of antibiotics among hospitalized patients: A multicenter, cross-sectional study in Lahore, Pakistan
(Public Library of Science, 2018)Background and objectives Adverse drug events (ADEs) are the fifth leading cause of death and thus responsible for a large number of hospital admissions in all over the globe. This study was aimed to assess the antibiotics ...