Clinical Pharmacy
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cRGD-Peptide Modified Covalent Organic Frameworks for Precision Chemotherapy in Triple-Negative Breast Cancer
(American Chemical Society, 2024)This study presents the use of nanoscale covalent organic frameworks (nCOFs) conjugated with tumor-targeting peptides for the targeted therapy of triple-negative breast cancer (TNBC). While peptides have previously been ... -
Knowledge and attitude towards vaginoplasty and perineoplasty among Jordanian females
(University of Jordan,Deanship of Scientific Research, 2024)Introduction: The global increase in female genital cosmetic surgery (FGCS), including procedures like vaginoplasty and perineoplasty, has raised concerns regarding their safety and effectiveness. Therefore, this study ... -
Exploring pharmacists’ attitude, willingness and barriers to provide extended community pharmacy services: Implications for improved pharmacy services
(Public Library of Science, 2024)Objective This study aimed to evaluate pharmacists’ attitude and willingness to provide extended community pharmacy services (ECPS), the barriers to ECPS, and the factors associated with attitude and willingness to implement ... -
Luteolin as potential treatment for Huntington's disease: Insights from a transgenic mouse model
(John Wiley and Sons Inc, 2024)Aims: The study aimed to evaluate the potential benefits of luteolin treatment in Huntington's disease (HD), an inherited progressive neurodegenerative disorder. Methods: HD N171-82Q transgenic and WT mice received luteolin ... -
Prevalence and predictors of hypoglycemia in older outpatients with type 2 diabetes mellitus
(Public Library of Science, 2024)Background The prevalence of type 2 diabetes (DM) has been increasing globally, particularly among older adults who are more susceptible to DM-related complications. Elderly individuals with diabetes are at higher risk of ... -
Advancements and Challenges in Antiamyloid Therapy for Alzheimer's Disease: A Comprehensive Review
(Hindawi Limited, 2024)Alzheimer's disease (AD) is a progressive neurodegenerative disorder caused by the accumulation of amyloid-beta (Aβ) proteins and neurofibrillary tangles in the brain. There have been recent advancements in antiamyloid ... -
Cellular and functional evaluation of LDLR missense variants reported in hypercholesterolemic patients demonstrates their hypomorphic impacts on trafficking and LDL internalization
(Frontiers Media SA, 2024)Background: Familial hypercholesterolemia (FH) is an autosomal dominant disorder characterized by increased LDL-cholesterol levels. About 85% of FH cases are caused by LDLR mutations encoding the low-density lipoprotein ... -
Community Pharmacists’ Perceptions of the most Important Interventions Implemented in Supporting Breastfeeding Women During Maternal Life: A Cross-Sectional Study in Jordan
(University of Jordan,Deanship of Scientific Research, 2024)Objectives: The purpose of this cross-sectional study is to investigate and analyze community pharmacists' perspectives on the most essential interventions implemented to support breastfeeding women during their maternal ... -
A retrospective analysis of the pharmacovigilance data registry in a tertiary teaching hospital in Jordan
(Taylor and Francis Ltd., 2024)Objectives: The study aims to analyse adverse drug reaction (ADR) reporting patterns at Jordan University Hospital to enhance pharmacovigilance practices. Methods: Retrospective analysis of ADR data from February to August ... -
Predictors of methotrexate adherence and patient's awareness of it in rheumatoid arthritis and its effect on quality of life
(Taylor and Francis Ltd., 2024)Introduction: Adherence studies among rheumatoid arthritis (RA) patients, in Egypt and throughout the Middle East region, are lacking. This study aimed to evaluate methotrexate (MTX) adherence in Rheumatoid arthritis (RA) ... -
The pharmacists’ interventions after a Drug and Therapeutics Committee (DTC) establishment during the COVID-19 pandemic
(Taylor and Francis Ltd., 2024)Introduction: Healthcare systems in developing countries faced significant challenges during COVID-19, grappling with limited resources and staffing shortages. Assessment of the impact of pharmaceutical care expertise, ... -
Prevalence of key potentially inappropriate drugs use in pediatrics: a cross-sectional study
(BioMed Central Ltd, 2024)Background: Appropriate drug prescribing in the pediatric population is challenging, given this age group’s unique pharmacokinetics. This has inevitably led to a high incidence of adverse drug reactions in this population. ... -
Assessment of knowledge and awareness of stroke among the Syrian population: unveiling the current landscape in Syria through the first nationally representative study
(Nature Research, 2024)Stroke is a global public health concern, contributing to high rates of morbidity and mortality. In Syria, the current conflict and associated challenges have had a profound impact on healthcare infrastructure, including ... -
Medication non-adherence among outpatients with myocardial infarction: A hospital-based study
(Elsevier B.V., 2024)Background: Despite the availability of effective medications for the treatment of myocardial infarction (MI), treatment outcomes are suboptimal due to medication non-adherence. The aim of this study was to assess medication ... -
Current Perspectives, Practices, and Barriers Faced by Community Pharmacists Regarding Pharmaceutical Care Services for Diabetes Mellitus in the United Arab Emirates
(Dove Medical Press Ltd, 2024)Background: Providing accurate and sufficient information is a crucial requirement for delivering effective diabetes care, making it essential for community pharmacists to possess adequate knowledge of diabetes mellitus ... -
Determinants of Health-Related Quality of Life in Outpatients with Myocardial Infarction
(Dove Medical Press Ltd, 2024)Background: The health-related quality of life (HRQOL) of patients with myocardial infarction (MI) is suboptimal because of the disease’s life-threatening nature, the requirement for long-term lifestyle modifications, and ... -
Lipid and Glucose Profile across Different Mental Disorders
(Multidisciplinary Digital Publishing Institute (MDPI), 2024-05)Objectives: Schizophrenia, unipolar depression, bipolar disorder, bipolar mania, and bipolar depression are a few of the severe psychiatric diseases that affect millions of individuals and their overall life quality. This ... -
Hospital pharmacists’ knowledge, attitudes and practice of pharmaceutical care and the barriers for its implementation at the hospital setting
(Elsevier Ltd, 2024-04-30)Objective: To assess hospital pharmacists' understanding of pharmaceutical care and their attitudes regarding the adoption of the patient-centered model, as well as investigate Jordan's current state of pharmaceutical care ... -
Acceptance of Flu Vaccine among Parents of Diabetic Children in Jordan
(Multidisciplinary Digital Publishing Institute (MDPI), 2024)There is a critical need to understand vaccine decision-making in high-risk groups. This study explored flu vaccine acceptance among Jordanian parents of diabetic children. Employing a cross-sectional approach, 405 parents ... -
Community pharmacist-led point-of-care eGFR screening: early detection of chronic kidney disease in high-risk patients
(Nature Research, 2024)Adherence to scheduled physician screenings for renal function monitoring in patients with chronic kidney disease (CKD) or those at high risk remains suboptimal despite the endorsement of regular screenings by several ...