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Computer-aided approaches reveal trihydroxychroman and pyrazolone derivatives as potential inhibitors of SARS-CoV-2 virus main protease
(Sciendo, 2021)
COVID-19 was declared a pandemic by the World Health Organization (WHO) in March 2020. The disease is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The aim of this study is to target the SARS-CoV-2 ...
Formulation and Evaluation of Linum usitatissimum Mucilage-Based Nanoparticles for Effective Delivery of Ezetimibe
(Dove Medical Press Ltd., 2021)
Introduction: The aim of current study was to prepare Linum usitatissimum mucilage (LUM) based nanoparticles, capable of encapsulating hydrophobic drug ezetimibe as nanocarriers. Methods: Solvent evaporation and nanoprecipitation ...
A quantitative evaluation of evidence-based beliefs and implementation among community pharmacists: Findings and impact from United Arab Emirates
(Dove Medical Press Ltd., 2021)
Background: The flux of pharmaceutical data can have a negative impact on the complexity of a pharmacist’s decision-making process, which will demand an extensive evaluation from healthcare providers trying to choose the ...
How to face COVID-19: proposed treatments based on remdesivir and hydroxychloroquine in the presence of zinc sulfate. Docking/DFT/POM structural analysis
(Taylor and Francis Ltd., 2021)
Remdesivir and hydroxychloroquine derivatives form two important classes of heterocyclic compounds. They are known for their anti-malarial biological activity. This research aims to analyze the physicochemical properties ...
The evolving role of community pharmacists during COVID-19 in the UAE; assessing preparedness and knowledge
(Oxford University Press, 2021)
Objectives To investigate community pharmacists' knowledge about COVID-19 and their preparedness for the pandemic. Methods This cross-sectional online survey was conducted (in community pharmacies in the United Arab Emirates) ...
Defect in phosphoinositide signalling through a homozygous variant in PLCB3 causes a new form of spondylometaphyseal dysplasia with corneal dystrophy
(JMDGA., 2021)
Background Bone dysplasias are a large group of disorders affecting the growth and structure of the skeletal system. Methods In the present study, we report the clinical and molecular delineation of a new form of syndromic ...
β-cyclodextrin chitosan-based hydrogels with tunable pH-responsive properties for controlled release of acyclovir: design, characterization, safety, and pharmacokinetic evaluation
(Taylor and Francis Ltd., 2021)
In this work, series of pH-responsive hydrogels (FMA1–FMA9) were synthesized, characterized, and evaluated as potential carrier for oral delivery of an antiviral drug, acyclovir (ACV). Different proportions of β-cyclodextrin ...
iOntoBioethics: A Framework for the Agile Development of Bioethics Ontologies in Pandemics, Applied to COVID-19
(Frontiers Media S.A., 2021)
Background: Few ontological attempts have been reported for conceptualizing the bioethics domain. In addition to limited scope representativeness and lack of robust methodological approaches in driving research design and ...
Online medication purchasing during the Covid-19 pandemic: A pilot study from the United Arab Emirates
(Springer, 2021)
Abstract
Background: Since the WHO announced that Covid-19 had become a global pandemic, online pharmacies have
emerged as an extremely popular way to purchase medication due to the quarantine measures introduced by ...
The investigation of energy management and atomic interaction between coronavirus structure in the vicinity of aqueous environment of H2O molecules via molecular dynamics approach
(Elsevier B.V., 2021)
The coronavirus pandemic is caused by intense acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Identifying the atomic structure of this virus can lead to the treatment of related diseases in medical cases. In the ...