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Thiolated cyclodextrins: Mucoadhesive and permeation enhancing excipients for ocular drug delivery
(Elsevier B.V., 2021)
Thiolated β-cyclodextrin (β-CD) has the potential to enhance mucoadhesive and permeation enhancing properties on ocular mucosa. Thiolated β-CD was synthesized via replacement of all primary hydroxyl groups on β-CD backbone ...
Micro-RNAs in the regulation of immune response against SARS CoV-2 and other viral infections
(Elsevier B.V., 2021)
Background: Micro-RNAs (miRNAS) are non-coding, small RNAs that have essential roles in different biological processes through silencing genes, they consist of 18–24 nucleotide length RNA molecules. Recently, miRNAs have ...
The ratio of eicosapentaenoic acid to docosahexaenoic acid as a modulator for the cardio-metabolic effects of omega-3 supplements: A meta-regression of randomized clinical trials
(Churchill Livingstone, 2021)
Background: A large number of studies have demonstrated the effects of omega- 3 supplements containing mixtures of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), known to favorably affect many modifiable risk ...
Immune system response during viral Infections: Immunomodulators, cytokine storm (CS) and Immunotherapeutics in COVID-19
(Elsevier B.V., 2021)
Coronaviruses are non-segmented and single stranded positive-sense RNA (+ssRNA) viruses. To date, 06 human coronaviruses (HCoVs) are reported; α-CoVs (HCoVs-NL63 and HCoVs-229E) and β-CoVs (HCoVs-OC43, HCoVs-HKU1, SARS-CoV, ...
Application of the American College of Cardiology (ACC/AHA) 2017 Guideline for the Management of Hypertension in Adults and Comparison with the 2014 Eighth Joint National Committee Guideline
(Saudi Heart Association, 2021)
Objectives: This study aims to compare the 2017-ACC/AHA hypertension guideline with 2014-JNC-8 guideline in re-gard to the number of patients who are eligible for treatment and to determine the physicians’ adherence and ...
Assessment of extrapyramidal symptoms associated with psychotropics pharmacological treatments, and associated risk factors
(Bentham Science Publishers, 2021)
Background: Extrapyramidal Symptoms (EPS) are unwanted symptoms commonly originating from the use of certain medications. The symptoms can range from minimal discomfort to permanent involuntary muscular movements. The aims ...
The Era of E-Cigarettes: A Cross-Sectional Study of Vaping Preferences, Reasons for Use and Withdrawal Symptoms Among Current E-Cigarette Users in the United Arab Emirates
(Springer, 2021)
Electronic cigarette (E-cig) use has increased substantially among the young population, who adopt using E-cig for various reasons. Our present study aimed to explore vaping preferences and reasons for using E-cig among ...
COVID-19 pandemic and transmission factors: An empirical investigation of different countries
(John Wiley and Sons Ltd, 2021)
The present work evaluates the impact of age, population density, total population, rural population, annual average temperature, basic sanitation facilities, and diabetes prevalence on the transmission of COVID-19. This ...
Circulating and local nuclear expression of survivin and fibulin-3 genes in discriminating benign from malignant respiratory diseases: correlation analysis
(Portland Press Ltd, 2021)
Survivin is an inhibitor of apoptosis as well as a promoter of cell proliferation. Fibulin-3 is a matrix glycoprotein that displays potential for tumor suppression or propagation. The present study aimed to validate the ...
Optimal control analysis of hepatitis B virus with treatment and vaccination
(Elsevier B.V., 2020)
Hepatitis B infection is one of the global health problems and potentially life-threatening liver infection. This infection is preventable and can be controlled using vaccination and proper treatment. The mathematical ...