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The flavonoid luteolin reduces mutant huntingtin aggregation and cytotoxicity in huntingtin-mutated neuroblastoma cells
(Elsevier B.V., 2023-12)
Background: Huntington's disease is an inherited progressive neurodegenerative disorder caused by an expansion of the polyglutamine tract leading to malformation and aggregation of the mutant huntingtin protein in the cell ...
Exploring knowledge, attitudes, and practices towards artificial intelligence among health professions’ students in Jordan
(BioMed Central Ltd, 2023-12)
Introduction: The integration of Artificial Intelligence (AI) in medical education and practice is a significant development. This study examined the Knowledge, Attitudes, and Practices (KAP) of health professions’ students ...
Behavioral dualism of endophytes in plant-microbe interaction and their diverse applications - a review
(Slovak University of Agriculture, 2023)
Microbes are harmful as well as beneficial for the human, plants and environment. Plant-microbe interaction array depicts both mutualism and pathogenesis. This dual nature of microbes depends on their surrounding abiotic ...
Evaluation of anticancer potential of tetracene-5,12-dione (A01) and pyrimidine-2,4-dione (A02) via caspase 3 and lactate dehydrogenase cytotoxicity investigations
(Public Library of Science, 2023-12)
Cancer stands as a significant global cause of mortality, predominantly arising from the dysregulation of key enzymes and DNA. One strategic avenue in developing new anticancer agents involves targeting specific proteins ...
Augmenting Fertility in Anestrus and Subestrus Cows with Hormonal Interventions and Their Effect on Blood Biochemical Profile
(ACS Publisher, 2022)
A study was carried out on forty-four problem breeder cows to evaluate the therapeutic efficacy of GnRH and PGF2α for estrus induction response, treatment to estrus induction interval and conception rate and its effect on ...
Development and Characterization of Thiolated Cyclodextrin-Based Nanoparticles for Topical Delivery of Minoxidil
(Multidisciplinary Digital Publishing Institute (MDPI), 2023-12)
Purpose: The aim of this research was to prepare adhesive nanoparticles for the topical application of Minoxidil (MXD). Methods: Thiolated β-CDs were prepared via conjugation of cysteamine with oxidized CDs. MXD was ...
Relation between myostatin levels and malnutrition and muscle wasting in hemodialysis patients
(PubMed ID, 2023-12-20)
BACKGROUND AND AIM: Malnutrition is one of the most troublesome comorbidities among hemodialysis patients (HD). Myostatin (MSTN) belongs to the transforming growth factor-β superfamily. In HD patients, MSTN effects are not ...
Cytotoxicity, Antioxidant Activity and Phytochemical Screening of Four Euphorbia Species from Jordan
(Faculty of Pharmacy, University of Benin, 2023-12-31)
The current study was designed to reveal the main groups of secondary metabolites in the methanol (M) and acetone (A) extracts from four Euphorbia species from Jordan. The extracts of these species were also tested for ...
Apolipoprotein E Genetic Variant and Blood Lipid Responses to Plant Sterols: A Systematic Review and Pooled Analysis of Clinical Trials
(Korean Society of Food Science and Nutrition, 2023-12)
Plant sterols/stanols are effective cholesterol-lowering agents. However, it is unclear whether the apolipoprotein E (ApoE) genetic variants influence it. We investigated whether ApoE genetic variants modulate the responses ...
Rheumatoid Arthritis Treatment Potential of Stearic Acid Nanoparticles of Quercetin in Rats
(American Chemical Society, 2023)
This study aims to assess the anti-inflammatory potential of stearic acid nanoparticles of quercetin in an arthritic rat model. This article describes the fabrication of solid lipid nanoparticles (SLNs) using the hot melt ...