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A new hydrophobic deep eutectic solvent composed of menthol and tris(2-ethylhexyl) phosphate for solvent bar microextraction of parabens from biological fluids
(KeAi Communications Co., 2024-06)
Parabens are antimicrobial preservatives with extensive applications in cosmetics, toiletries, pharmaceuticals, and food. Considering the legitimate concerns relating to their potential to disrupt multiple endocrine ...
Apolipoprotein E Genetic Variant and Blood Lipid Responses to Plant Sterols: A Systematic Review and Pooled Analysis of Clinical Trials
(Korean Society of Food Science and Nutrition, 2023-12)
Plant sterols/stanols are effective cholesterol-lowering agents. However, it is unclear whether the apolipoprotein E (ApoE) genetic variants influence it. We investigated whether ApoE genetic variants modulate the responses ...
Rheumatoid Arthritis Treatment Potential of Stearic Acid Nanoparticles of Quercetin in Rats
(American Chemical Society, 2023)
This study aims to assess the anti-inflammatory potential of stearic acid nanoparticles of quercetin in an arthritic rat model. This article describes the fabrication of solid lipid nanoparticles (SLNs) using the hot melt ...
Prevalence of Medication Associated with QTc Prolongation Used Among Critically Ill Patients
(Dove Medical Press Ltd, 2024)
Background: Acquired prolonged corrected QT (QTc) interval can lead to life-threatening Torsade de Pointes (TdP) arrhythmia. Multiple risk factors including medications, comorbidities, and electrolyte imbalances contribute ...
Modulating the majority charge carrier type and performance of organic heterojunction ammonia sensors by increasing peripheral fluorination of the silicon phthalocyanine sublayer
(Elsevier B.V., 2024-06-01)
Silicon phthalocyanines (R2-SiPcs) are an emerging class of high-performance organic semiconductors which have recently found application in highly sensitive and selective bilayer organic heterojunction devices for ammonia ...
In-silico characterization of GABAT protein found in gut-brain axis associated bacteria of healthy individuals and multiple sclerosis patients
(Elsevier B.V., 2024-04)
Background: Multiple sclerosis (MS) is a neurodegenerative disease characterized by inflammation and demyelination of neurons. There is evidence to suggest that level of a neurotransmitter gamma-aminobutyric acid (GABA), ...
The impact of COVID-19 on treatment followup and medication adherence among patients with epilepsy at a referral hospital in Ethiopia
(Public Library of Science, 2024-02)
Background The world continues to be challenged by the Coronavirus disease 2019 (COVID-19) and preventive measures like maintaining social distancing and lockdowns challenge patients to attend regular follow-ups and get a ...
Environmental and personal barriers encountered in community pharmacy settings based on public opinions
(Future Science Ltd, 2024-01-01)
Aim: We aimed in this study to assess the potential environmental and personal barriers encountered in the community pharmacies in Jordan. Methods: A validated self-administered survey was distributed online to 721 ...
Preparation and Characterization of Theophylline Controlled Release Matrix System Incorporating Poloxamer 407, Stearyl Alcohol, and Hydroxypropyl Methylcellulose: A Novel Formulation and Development Study
(Multidisciplinary Digital Publishing Institute (MDPI), 2024-03)
Background: Theophylline (THN), a bronchodilator with potential applications in emerging conditions like COVID-19, requires a controlled-release delivery system due to its narrow therapeutic range and short half-life. This ...
Lavandula stoechas significantly alleviates cigarette smoke-induced acute lung injury via modulation of oxidative stress and the NF-κB pathway
(Elsevier Ltd, 2024-06)
Cigarette smoke (CS) is one of the major triggering factorsfor oxidative stress and contributes to development of acute lung injury and acute respiratory distress syndrome (ALI/ARDS), both of which are marked by severe ...