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The flavonoid luteolin reduces mutant huntingtin aggregation and cytotoxicity in huntingtin-mutated neuroblastoma cells
(Elsevier B.V., 2023-12)
Background: Huntington's disease is an inherited progressive neurodegenerative disorder caused by an expansion of the polyglutamine tract leading to malformation and aggregation of the mutant huntingtin protein in the cell ...
Novel carbon quantum dots incorporated polyacrylic acid/polyethylene glycol pH-sensitive nanoplatform for drug delivery
(Elsevier B.V., 2024-01)
Quercetin (Qc) is a safe plant metabolite that plays an effective role as a chemical inhibitor against tumor cells and in preventing the progression of many cancers. In this research, carbon quantum dots (CQDs) dispersed ...
Exploring knowledge, attitudes, and practices towards artificial intelligence among health professions’ students in Jordan
(BioMed Central Ltd, 2023-12)
Introduction: The integration of Artificial Intelligence (AI) in medical education and practice is a significant development. This study examined the Knowledge, Attitudes, and Practices (KAP) of health professions’ students ...
Behavioral dualism of endophytes in plant-microbe interaction and their diverse applications - a review
(Slovak University of Agriculture, 2023)
Microbes are harmful as well as beneficial for the human, plants and environment. Plant-microbe interaction array depicts both mutualism and pathogenesis. This dual nature of microbes depends on their surrounding abiotic ...
Evaluation of anticancer potential of tetracene-5,12-dione (A01) and pyrimidine-2,4-dione (A02) via caspase 3 and lactate dehydrogenase cytotoxicity investigations
(Public Library of Science, 2023-12)
Cancer stands as a significant global cause of mortality, predominantly arising from the dysregulation of key enzymes and DNA. One strategic avenue in developing new anticancer agents involves targeting specific proteins ...
Endophytic Bacillus spp. from native chilli cultivars and their effect against fruit rot pathogen of Bhut Jolokia (Capsicum chinense Jacq.)
(Springer Science and Business Media Deutschland GmbH, 2024-12)
Background: Fruit rot disease is one of the most important factors limiting the production potential of Bhut Jolokia (Capsicum chinense Jacq.), which is known as one of the hottest chillies in the world. The management ...
Augmenting Fertility in Anestrus and Subestrus Cows with Hormonal Interventions and Their Effect on Blood Biochemical Profile
(ACS Publisher, 2022)
A study was carried out on forty-four problem breeder cows to evaluate the therapeutic efficacy of GnRH and PGF2α for estrus induction response, treatment to estrus induction interval and conception rate and its effect on ...
Using hypnotic suggestion in the rehabilitation of working memory capacity after acquired brain injury: study protocol for a randomized controlled trial
(BioMed Central Ltd, 2024-12)
Objectives: Establishment of effective evidence-based interventions in rehabilitation of working memory (WM) deficits after acquired brain injury (ABI) is sorely needed. Despite robust evidence for the efficiency of clinical ...
Development and Characterization of Thiolated Cyclodextrin-Based Nanoparticles for Topical Delivery of Minoxidil
(Multidisciplinary Digital Publishing Institute (MDPI), 2023-12)
Purpose: The aim of this research was to prepare adhesive nanoparticles for the topical application of Minoxidil (MXD). Methods: Thiolated β-CDs were prepared via conjugation of cysteamine with oxidized CDs. MXD was ...
An epidemiological model for analysing pandemic trends of novel coronavirus transmission with optimal control
(Taylor and Francis Ltd., 2024)
Symptomatic and asymptomatic individuals play a significant role in the transmission dynamics of novel Coronaviruses. By considering the dynamical behaviour of symptomatic and asymptomatic individuals, this study examines ...