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Antimicrobial prospect of newly synthesized 1,3-thiazole derivatives
(MDPI AG., 2011)
A new series of 1,3-thiazole and benzo[d] thiazole derivatives 10-15 has been developed, characterized, and evaluated for in vitro antimicrobial activity at concentrations of 25-200 μg/mL against Gram+ve organisms such as ...
Experiential community pharmacy training: Assessment of students’ perceptions in the united arab emirates
(International Pharmaceutical Federation, 2020)
Introduction: Community pharmacy settings provide places for promoting the effective and safe use of medicines all over the world. This study explored pharmacy students’ perceptions of the barriers they had faced during ...
Factors affecting the development of adverse drug reactions (Review article)
(Elsevier, 2013)
Objectives: To discuss the effect of certain factors on the occurrence of Adverse Drug Reactions (ADRs). Data Sources: A systematic review of the literature in the period between 1991 and 2012 was made based on PubMed, the ...
The pharmacological basis of Cuscuta reflexa whole plant as an antiemetic agent in pigeons
(Elsevier Inc., 2020)
Cuscuta reflexa has been traditionally used as an antiemetic. Additionally, it has been used in various herbal formulations for the treatment of emesis. So far, there is no scientific evidence of the plant extract as ...
Novel thiosemicarbazides induced apoptosis in human MCF-7 breast cancer cells via JNK signaling
(Taylor and Francis Ltd., 2015)
In this study, novel thiosemicarbazides and 1,3,4-oxadiazoles were synthesized and evaluated for their anticancer effects on human MCF-7 breast cancer cell lines. Among the synthesized derivatives studied, compound ...
Direct interactions with both p27 and Cdk2 regulate Spy1-mediated proliferation in vivo and in vitro
(Taylor and Francis Inc., 2016)
Families of cyclin-like proteins have emerged that bind and activate cyclin dependent kinases (Cdk)s, directing the phosphorylation of noncanonical Cdk substrates. One of these proteins, Spy1, has demonstrated the unique ...
Formulation and Evaluation of Linum usitatissimum Mucilage-Based Nanoparticles for Effective Delivery of Ezetimibe
(Dove Medical Press Ltd., 2021)
Introduction: The aim of current study was to prepare Linum usitatissimum mucilage (LUM) based nanoparticles, capable of encapsulating hydrophobic drug ezetimibe as nanocarriers. Methods: Solvent evaporation and nanoprecipitation ...
COVID-19 Vaccine Development in a Quadruple Helix Innovation System: Uncovering the Preferences of the Fourth Helix in the UAE
(MDPI AG., 2020)
Successful development and uptake of vaccine technology in a Quadruple Helix Innovative health or economic system requires a clear understanding of society’s preferences as the fourth helix. With significant financial ...
Druggability analysis and classification of protein tyrosine phosphatase active sites
(Dove Medical Press Ltd., 2016)
Protein tyrosine phosphatases (PTP) play important roles in the pathogenesis of many diseases. The fact that no PTP inhibitors have reached the market so far has raised many questions about their druggability. In this ...
Evaluation of certain pharmaceutical quality attributes of lisinopril split tablets
(MDPI AG., 2016)
Tablet splitting is an accepted practice for the administration of drugs for a variety of reasons, including dose adjustment, ease of swallowing and cost savings. The purpose of this study was to evaluate the physical ...