Browsing Pharmaceutical Sciences by Title
Now showing items 100-119 of 146
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Nonsteroidal Anti-inflammatory Drugs Utilization Patterns and Risk of Adverse Events due to Drug-Drug Interactions among Elderly Patients: A Study from Jordan
(Elsevier B.V., 2020)Background: Worldwide, the prescribing pattern of the Nonsteroidal Anti-inflammatory Drugs (NSAIDs) has increased. They are considered highly effective medications in controlling various conditions including inflammatory ... -
Novel carbon quantum dots incorporated polyacrylic acid/polyethylene glycol pH-sensitive nanoplatform for drug delivery
(Elsevier B.V., 2024-01)Quercetin (Qc) is a safe plant metabolite that plays an effective role as a chemical inhibitor against tumor cells and in preventing the progression of many cancers. In this research, carbon quantum dots (CQDs) dispersed ... -
Novel N-phenylcarbamothioylbenzamides with anti-inflammatory activity and prostaglandin E2 inhibitory properties
(PubMed ID., 2013)A number of 2-((4-ethylphenoxy)methyl)-N-(substituted-phenylcarbamothioyl)benzamides (1a-h) were synthesized via reaction of 2-((4-ethylphenoxy)methyl)benzoyl isothiocyanate (2) as a key intermediate with several substituted ... -
Novel thiosemicarbazides induced apoptosis in human MCF-7 breast cancer cells via JNK signaling
(Taylor and Francis Ltd., 2015)In this study, novel thiosemicarbazides and 1,3,4-oxadiazoles were synthesized and evaluated for their anticancer effects on human MCF-7 breast cancer cell lines. Among the synthesized derivatives studied, compound ... -
Nurses perception of pharmaceutical care practice: A qualitative approach
(University of Benin, 2020)Purpose: To evaluate the perception of nurses regarding pharmaceutical care services in the healthcare system of Khyber Pakhtunkhwa (KPK) Province of Pakistan. Methods: This qualitative study was implemented by conducting ... -
Nurses’ Perceptions, Involvement, Confidence and Perceived Barriers Towards Antimicrobial Stewardship Program in Pakistan: Findings from a Multi-Center, Cross-Sectional Study
(Dove Medical Press Ltd, 2022)Purpose: Antimicrobial resistance (AMR) is leading to greater therapeutic cost, length of hospital stays, adverse events, morbidity and mortality. Hospital-based antimicrobial stewardship programs (ASPs) engaging physicians, ... -
Online medication purchasing during the Covid-19 pandemic: A pilot study from the United Arab Emirates
(Springer, 2021)Abstract Background: Since the WHO announced that Covid-19 had become a global pandemic, online pharmacies have emerged as an extremely popular way to purchase medication due to the quarantine measures introduced by ... -
Papain-Decorated Mucopenetrating SEDDS: A Tentative Approach to Combat Absorption Issues of Acyclovir via the Oral Route
(MDPI, 2022)The aim of the current study was to enhance the oral bioavailability of Acyclovir (ACV) based on the papain-functionalized self-emulsifying drug delivery systems (SEDDS). The optimum control SEDDS formulation comprised of ... -
The patterns of herbal medicine use in the United Arab Emirates; A national study
(Grupo de Investigacion en Atencion Farmaceutica, 2022)Objectives: To examine the pattern, nature, and attitude towards herbal medicines usage in the UAE. Methods: A cross-sectional national questionnaire was distributed over five weeks in 7 emirates of UAE: The questioner was ... -
Paving Luteolin Therapeutic Potentialities and Agro-Food-Pharma Applications: Emphasis on in Vivo Pharmacological Effects and Bioavailability Traits
(Hindawi Limited, 2021)Luteolin is a naturally occurring secondary metabolite belonging to the class of flavones. As many other natural flavonoids, it is often found in combination with glycosides in many fruits, vegetables, and plants, contributing ... -
Pharmacokinetic interaction of rosuvastatin with artichoke (Cynara scolymusL.) leaf extract in rats
(Open Science Publishers LLP Inc., 2023)Dyslipidemia is a prevalent disease among the international population that has substantially increased, which can be treated with several hypolipidemic drugs such as rosuvastatin. Artichoke is a plant that is commonly ... -
The pharmacological basis of Cuscuta reflexa whole plant as an antiemetic agent in pigeons
(Elsevier Inc., 2020)Cuscuta reflexa has been traditionally used as an antiemetic. Additionally, it has been used in various herbal formulations for the treatment of emesis. So far, there is no scientific evidence of the plant extract as ... -
Pharmacological Validation for the Folklore Use of Ipomoea nil against Asthma: In Vivo and In Vitro Evaluation
(NLM (Medline), 2022)Oxidative stress is the key factor that strengthens free radical generation which stimulates lung inflammation. The aim was to explore antioxidant, bronchodilatory along with anti-asthmatic potential of folkloric plants ... -
Phytochemical profiling, antioxidant and antiproliferation potential of Euphorbia milii var.: Experimental analysis and in-silico validation
(Elsevier B.V., 2020)This study was aimed to investigate the anticancer potential of Euphorbia milii (E. milii) using an exquisite combination of phytopharmacological and advanced computational techniques. The chloroform fraction (Em-C) of E. ... -
Polyvinylpyrrolidone K-30-Based Crosslinked Fast Swelling Nanogels: An Impeccable Approach for Drug's Solubility Improvement
(NLM (Medline), 2022)Poor solubility is a global issue of copious pharmaceutical industries as large number of drugs in development stage as well as already marketed products are poorly soluble which results in low dissolution and ultimately ... -
Potential strategies for combating COVID-19
(Springer, 2020)Coronavirus disease 2019, also known as COVID-19, is caused by a novel coronavirus named severe acute respiratory syndrome coronavirus 2, or SARS-CoV-2. The infection has now catapulted into a full-blown pandemic across ... -
Prediction of lisinopril pediatric dose from the reference adult dose by employing a physiologically based pharmacokinetic model
(BioMed Central, 2020)Background: This study aimed to assess the pediatric lisinopril doses using an adult physiological based pharmacokinetic (PBPK) model. As the empirical rules of dose calculation cannot calculate gender-specific pediatric ... -
Preliminary Investigation of Linum usitatissimum Mucilage-Based Hydrogel as Possible Substitute to Synthetic Polymer-Based Hydrogels for Sustained Release Oral Drug Delivery
(MDPI, 2022)The aim of this study was to investigate the potential of Linum usitatissimum mucilage, a natural polymer, in developing a sustained release hydrogel for orally delivered drugs that require fre-quent dosing. For this ... -
Preparation and Characterization of Theophylline Controlled Release Matrix System Incorporating Poloxamer 407, Stearyl Alcohol, and Hydroxypropyl Methylcellulose: A Novel Formulation and Development Study
(Multidisciplinary Digital Publishing Institute (MDPI), 2024-03)Background: Theophylline (THN), a bronchodilator with potential applications in emerging conditions like COVID-19, requires a controlled-release delivery system due to its narrow therapeutic range and short half-life. This ... -
Proanthocyanidins: A comprehensive review
(Elsevier Masson SAS., 2019)Proanthocyanidins are condensed tannins with various pharmacological properties. These phytochemicals are considered as ‘offense and defense molecules because of their human health benefits. The validation of their diverse ...