Browsing Pharmaceutical Sciences by Title
Now showing items 91-110 of 146
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Nanomedicines: Emerging Platforms in Smart Chemotherapy Treatment—A Recent Review
(Multidisciplinary Digital Publishing Institute (MDPI), 2024-03)Cancer continues to pose one of the most critical challenges in global healthcare. Despite the wide array of existing cancer drugs, the primary obstacle remains in selectively targeting and eliminating cancer cells while ... -
Nanoparticles in clinical trials of COVID-19: An update
(Elsevier Ltd, 2022)Once the World Health Organization (WHO) declared the COVID-19 (Coronavirus Infectious Disease-19) outbreak to be pandemic, massive efforts have been launched by researchers around the globe to combat this emerging infectious ... -
Nanosized liposomes containing bile salt: A vesicular nanocarrier for enhancing oral bioavailability of BCS class III drug
(Canadian Society for Pharmaceutical Sciences, 2017)PURPOSE: Liposomes have been studied as a colloidal carrier in drug delivery systems, especially for oral administration. However, their low structural integrity in the gut is still a major shortcoming. Membrane disruptive ... -
Nanostructured lipid carriers based suppository for enhanced rectal absorption of ondansetron: In vitro and in vivo evaluations
(Elsevier B.V., 2021)The current research aimed to fabricate ondansetron nanostructured lipid carriers (OND-NLCs) and incorporate them into a suppository base to manage chemotherapy-induced vomiting and nausea, which offer the advantage of ... -
Nanotechnology-Based Drug Delivery Approaches of Mangiferin: Promises, Reality and Challenges in Cancer Chemotherapy
(Multidisciplinary Digital Publishing Institute (MDPI), 2023)Mangiferin (MGF), a xanthone derived from Mangifera indica L., initially employed as a nutraceutical, is now being explored extensively for its anticancer potential. Scientists across the globe have explored this bioactive ... -
A narrative review of approved and emerging anti-obesity medications
(Elsevier B.V., 2023)Background: Recently, many drugs have been approved for halting overweight and obesity—few types of research shifted to using Anti-obesity medications (AOM) solely for well-being and shape-keeping. Objective: This narrative ... -
A new hydrophobic deep eutectic solvent composed of menthol and tris(2-ethylhexyl) phosphate for solvent bar microextraction of parabens from biological fluids
(KeAi Communications Co., 2024-06)Parabens are antimicrobial preservatives with extensive applications in cosmetics, toiletries, pharmaceuticals, and food. Considering the legitimate concerns relating to their potential to disrupt multiple endocrine ... -
New Insights Into the Anticonvulsant Effects of Essential Oil From Melissa officinalis L. (Lemon Balm)
(Frontiers Media S.A., 2021)Melissa officinalis L. is used in traditional European and Iranian folk medicines to treat a plethora of neurological diseases including epilepsy. We utilized the in vitro and in vivo models of epilepsy to probe the ... -
Non Pharmaceutical Interventions for Optimal Control of COVID-19
(Elsevier, 2020)Background and Objective: The outbreak of the current pandemic begun from the first individual of a 55-year old from Hubei province in China, the disease instigated by the new coronavirus spreading across the world. ... -
Nonsteroidal Anti-inflammatory Drugs Utilization Patterns and Risk of Adverse Events due to Drug-Drug Interactions among Elderly Patients: A Study from Jordan
(Elsevier B.V., 2020)Background: Worldwide, the prescribing pattern of the Nonsteroidal Anti-inflammatory Drugs (NSAIDs) has increased. They are considered highly effective medications in controlling various conditions including inflammatory ... -
Novel carbon quantum dots incorporated polyacrylic acid/polyethylene glycol pH-sensitive nanoplatform for drug delivery
(Elsevier B.V., 2024-01)Quercetin (Qc) is a safe plant metabolite that plays an effective role as a chemical inhibitor against tumor cells and in preventing the progression of many cancers. In this research, carbon quantum dots (CQDs) dispersed ... -
Novel N-phenylcarbamothioylbenzamides with anti-inflammatory activity and prostaglandin E2 inhibitory properties
(PubMed ID., 2013)A number of 2-((4-ethylphenoxy)methyl)-N-(substituted-phenylcarbamothioyl)benzamides (1a-h) were synthesized via reaction of 2-((4-ethylphenoxy)methyl)benzoyl isothiocyanate (2) as a key intermediate with several substituted ... -
Novel thiosemicarbazides induced apoptosis in human MCF-7 breast cancer cells via JNK signaling
(Taylor and Francis Ltd., 2015)In this study, novel thiosemicarbazides and 1,3,4-oxadiazoles were synthesized and evaluated for their anticancer effects on human MCF-7 breast cancer cell lines. Among the synthesized derivatives studied, compound ... -
Nurses perception of pharmaceutical care practice: A qualitative approach
(University of Benin, 2020)Purpose: To evaluate the perception of nurses regarding pharmaceutical care services in the healthcare system of Khyber Pakhtunkhwa (KPK) Province of Pakistan. Methods: This qualitative study was implemented by conducting ... -
Nurses’ Perceptions, Involvement, Confidence and Perceived Barriers Towards Antimicrobial Stewardship Program in Pakistan: Findings from a Multi-Center, Cross-Sectional Study
(Dove Medical Press Ltd, 2022)Purpose: Antimicrobial resistance (AMR) is leading to greater therapeutic cost, length of hospital stays, adverse events, morbidity and mortality. Hospital-based antimicrobial stewardship programs (ASPs) engaging physicians, ... -
Online medication purchasing during the Covid-19 pandemic: A pilot study from the United Arab Emirates
(Springer, 2021)Abstract Background: Since the WHO announced that Covid-19 had become a global pandemic, online pharmacies have emerged as an extremely popular way to purchase medication due to the quarantine measures introduced by ... -
Papain-Decorated Mucopenetrating SEDDS: A Tentative Approach to Combat Absorption Issues of Acyclovir via the Oral Route
(MDPI, 2022)The aim of the current study was to enhance the oral bioavailability of Acyclovir (ACV) based on the papain-functionalized self-emulsifying drug delivery systems (SEDDS). The optimum control SEDDS formulation comprised of ... -
The patterns of herbal medicine use in the United Arab Emirates; A national study
(Grupo de Investigacion en Atencion Farmaceutica, 2022)Objectives: To examine the pattern, nature, and attitude towards herbal medicines usage in the UAE. Methods: A cross-sectional national questionnaire was distributed over five weeks in 7 emirates of UAE: The questioner was ... -
Paving Luteolin Therapeutic Potentialities and Agro-Food-Pharma Applications: Emphasis on in Vivo Pharmacological Effects and Bioavailability Traits
(Hindawi Limited, 2021)Luteolin is a naturally occurring secondary metabolite belonging to the class of flavones. As many other natural flavonoids, it is often found in combination with glycosides in many fruits, vegetables, and plants, contributing ... -
Pharmacokinetic interaction of rosuvastatin with artichoke (Cynara scolymusL.) leaf extract in rats
(Open Science Publishers LLP Inc., 2023)Dyslipidemia is a prevalent disease among the international population that has substantially increased, which can be treated with several hypolipidemic drugs such as rosuvastatin. Artichoke is a plant that is commonly ...