Browsing Pharmaceutical Sciences by Title
Now showing items 6-25 of 148
-
Apolipoprotein E Genetic Variant and Blood Lipid Responses to Plant Sterols: A Systematic Review and Pooled Analysis of Clinical Trials
(Korean Society of Food Science and Nutrition, 2023-12)Plant sterols/stanols are effective cholesterol-lowering agents. However, it is unclear whether the apolipoprotein E (ApoE) genetic variants influence it. We investigated whether ApoE genetic variants modulate the responses ... -
Application of the American College of Cardiology (ACC/AHA) 2017 Guideline for the Management of Hypertension in Adults and Comparison with the 2014 Eighth Joint National Committee Guideline
(Saudi Heart Association, 2021)Objectives: This study aims to compare the 2017-ACC/AHA hypertension guideline with 2014-JNC-8 guideline in re-gard to the number of patients who are eligible for treatment and to determine the physicians’ adherence and ... -
Applying medicines reconciliation indicators in two UK hospitals: a feasibility study
(Oxford University Press, 2021)ObjectivesThe aim of this study was to apply the Medicines reconciliation (MR) indicators and to assess their feasibility for use with patients on admission. MethodsThis is a mixed-methods study conducted in two large ... -
Artemisia species and artemisinin derivatives as antiviral agents against COVID-19. current knowledge: Chemistry, pharmacology and clinical evidence
(Romanian Society for Pharmaceutical Sciences, 2022)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been the reason behind the third zoonotic outbreak from the Coronaviridae family during the 21st century. COVID-19 was declared a pandemic by the WHO on 11 ... -
Assessment of extrapyramidal symptoms associated with psychotropics pharmacological treatments, and associated risk factors
(Bentham Science Publishers, 2021)Background: Extrapyramidal Symptoms (EPS) are unwanted symptoms commonly originating from the use of certain medications. The symptoms can range from minimal discomfort to permanent involuntary muscular movements. The aims ... -
Assessment of Knowledge, Perception, Experience and Phobia toward Corticosteroids Use among the General Public in the Era of COVID-19: A Multinational Study
(MDPI, 2023)Background: Corticosteroids play a significant role in managing the vast majority of inflammatory and immunologic conditions. To date, population-based studies on knowledge and attitudes concerning corticosteroids are ... -
Attitude, perception, willingness, motivation and barriers to practice-based research: A cross-sectional survey of hospital pharmacists in Lahore, Punjab, Pakistan
(Public Library of Science, 2018)Background and objectives Practice-based research (PBR) is of pivotal importance for hospital pharmacists which not only up-grades the profession but also improves the patient care. This study aimed to evaluate the attitude, ... -
Berberine as a Potential Anticancer Agent:A Comprehensive Review
(MDPI, 2021)Berberine (BBR), a potential bioactive agent, has remarkable health benefits. A substantial amount of research has been conducted to date to establish the anticancer potential of BBR. The present review consolidates salient ... -
Bioavailability of beclometasone from two hfa-bdp formulations with a spacer
(American Association for Respiratory, 2019)BACKGROUND: The drug delivery characteristics of each inhaler/spacer combination are unique. The spacer size as well as the presence of electrostatic charge greatly influence the inhaler dose emission and in vivo delivery. ... -
Bioequivalence assessment of two formulations of ibuprofen
(Dove Medical Press Ltd., 2011)Background: This study assessed the relative bioavailability of two formulations of ibuprofen. The first formulation was Doloraz ®, produced by Al-Razi Pharmaceutical Company, Amman, Jordan. The second forumulation was ... -
Biofunctional Hyaluronic Acid/κ-Carrageenan InjectableHydrogels for Improved Drug Delivery and Wound Healing
(MDPI, 2022)The in situ injectable hydrogel system offers a widespread range of biomedical applications in prompt chronic wound treatment and management, as it provides self-healing, maintains a moist wound microenvironment, and offers ... -
Biomimetic cell membrane-coated poly(lactic-co-glycolic acid) nanoparticles for biomedical applications
(John Wiley and Sons Inc, 2022)Poly(lactic-co-glycolic acid) (PLGA) nanoparticles (NPs) are commonly used for drug delivery because of their favored biocompatibility and suitability for sustained and controlled drug release. To prolong NP circulation ... -
Butylglyceryl pectin nanoparticles: Synthesis, formulation and characterization
(MDPI AG., 2019)Pectin is a polysaccharide with very good gel forming properties that traditionally has found important applications in foods and pharmaceutical industries. Although less studied, chemical modifications of pectin leading ... -
Carbopol Based Hydrogels for ITOPRIDE Hydrochloride Delivery; Synthesis, Characterization and Comparative Assessment with Various Monomers
(MDPI, 2022)The objective of the current study was to synthesize and characterize carbopol containing hydrogels with different monomers such as methacrylic acid (MAA), 2-acrylamido-2-methylpropane sulfonic acid (AMPS) and itaconic ... -
Characterization of human serum albumin's interactions with safranal and crocin using multi-spectroscopic and molecular docking techniques
(Elsevier B.V., 2019)Interaction mechanisms of human serum albumin (HSA) with safranal and crocin were studied using UV–Vis absorption, fluorescence quenching and circular dichroism (CD) spectroscopies as well as molecular docking techniques. ... -
Circulating Ubiquitin Carboxyl Terminal HydrolaseL1 and Neuroglobin Levels in Traumatic Spinal CordInjuries: Relation to Severity and Outcomes
(Dove Medical Press, 2022)Introduction: Traumatic spinal cord injury (TSCI) is a life-threatening neurological disorder and there is a lack of biomarker research, particularly human studies that could help to categorize the severity and predict the ... -
Comparative Molecular Dynamics Simulation of Aggregating and Non-Aggregating Inhibitor Solutions: Understanding the Molecular Basis of Promiscuity
(John Wiley and Sons Ltd., 2018)The presence of false positives in enzyme inhibition assays is a common problem in early drug discovery, especially for compounds that form colloid aggregates in solution. The molecular basis of these aggregates could not ... -
The Compulsory Licensing for Exploiting Patented COVID-19 Pharmaceutical Treatment: Legal Approaches of Some Arab Countries.
(Mary Ann Liebert Inc., 2021)This article deals with exploitation of a pharmaceutical patent to treat the novel coronavirus. The laws of several Arab nations, which regulate industrial property rights in regard to the use of compulsory licensing for ... -
Computer-aided approaches reveal trihydroxychroman and pyrazolone derivatives as potential inhibitors of SARS-CoV-2 virus main protease
(Sciendo, 2021)COVID-19 was declared a pandemic by the World Health Organization (WHO) in March 2020. The disease is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The aim of this study is to target the SARS-CoV-2 ... -
Computer-aided discovery of antimicrobial agents as potential enoyl acyl carrier protein reductase inhibitors
(University of Benin, 2017)Purpose: To perform a virtual screening for a set of drug-like ligand library against the Staphylococcus aureus enoyl acyl carrier protein reductase, saFabI. Methods: The virtual screening was conducted based on a previously ...