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Gephyrin and cyp2c9 genetic polymorphisms in patients with pharmacoresistant epilepsy
(Dove Medical Press Ltd., 2021)
Purpose: Gephyrin (GPHN) is an essential protein in the regulation of inhibitory postsy-naptic density and polymorphism in the corresponding gene may have a role in the development of pharmacoresistant epilepsy (PRE). For ...
Paving Luteolin Therapeutic Potentialities and Agro-Food-Pharma Applications: Emphasis on in Vivo Pharmacological Effects and Bioavailability Traits
(Hindawi Limited, 2021)
Luteolin is a naturally occurring secondary metabolite belonging to the class of flavones. As many other natural flavonoids, it is often found in combination with glycosides in many fruits, vegetables, and plants, contributing ...
New Insights Into the Anticonvulsant Effects of Essential Oil From Melissa officinalis L. (Lemon Balm)
(Frontiers Media S.A., 2021)
Melissa officinalis L. is used in traditional European and Iranian folk medicines to treat a plethora of neurological diseases including epilepsy. We utilized the in vitro and in vivo models of epilepsy to probe the ...