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In vitro and in vivo evaluation of oral controlled release formulation of bcs class i drug using polymer matrix system
(MDPI, 2021)
Diltiazem hydrochloride is a calcium channel blocker, which belongs to the family of benzothiazepines. It is commonly used to treat hypertension and atrial fibrillation. Even though the drug has high solubility, its high ...
Amphiphilic Alkylated Pectin Hydrogels for Enhanced Topical Delivery of Fusidic Acid: Formulation and In Vitro Investigation
(MDPI, 2022)
Hydrogels constructed of amphiphilically modified polysaccharides have attracted a lot of interest because of their potential to augment drug diffusion over the skin. This research describes the synthesis of amphiphilic ...
Papain-Decorated Mucopenetrating SEDDS: A Tentative Approach to Combat Absorption Issues of Acyclovir via the Oral Route
(MDPI, 2022)
The aim of the current study was to enhance the oral bioavailability of Acyclovir (ACV) based on the papain-functionalized self-emulsifying drug delivery systems (SEDDS). The optimum control SEDDS formulation comprised of ...
Biomimetic cell membrane-coated poly(lactic-co-glycolic acid) nanoparticles for biomedical applications
(John Wiley and Sons Inc, 2022)
Poly(lactic-co-glycolic acid) (PLGA) nanoparticles (NPs) are commonly used for drug delivery because of their favored biocompatibility and suitability for sustained and controlled drug release. To prolong NP circulation ...
Depression, anxiety, and stress among university students in Selangor, Malaysia during COVID-19 pandemics and their associated factors
(Public Library of Science, 2023)
Introduction This study aims to assess the impacts of COVID-19 pandemics among university students in Malaysia, by identifying the prevalence of depression, anxiety and stress among them and their respective predictors. ...