Browsing Publications by Author "Nazir, Imran"
Now showing items 1-3 of 3
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Enhanced Intestinal Permeability of Cefixime by Self-Emulsifying Drug Delivery System: In-Vitro and Ex-Vivo Characterization
Mahmood, Arshad; Khan, Laraib; Ijaz, Muhammad; Nazir, Imran; Naseem, Mahrukh; Tahir, Muhammad Azam; Aamir, Muhammad Naeem; Rehman, Masood Ur; Asim, Mulazim Hussain (NLM (Medline), 2023)BACKGROUND: Cefixime (CFX) belongs to a group of third-generation cephalosporin antibiotics with low water solubility and low intestinal permeability, which ultimately leads to significantly low bioavailability. AIM: This ... -
Enhanced Oral Bioavailability of Epalrestat SBE7-β-CD Complex Loaded Chitosan Nanoparticles: Preparation, Characterization and in-vivo Pharmacokinetic Evaluation
Alvi, Zunaira; Akhtar, Muhammad; Mahmood, Arshad; Ur-Rahman, Nisar; Nazir, Imran; Sadaquat, Hadia; Ijaz, Muhammad; Syed, Shahzada Khurram; Waqas, Muhammad Khurram; Wang, Yi (NLM (Medline), 2021)Background: Epalrestat (EPL) is a carboxylic acid derivative with poor aqueous solubility and its pharmacokinetic features are not fully defined. Purpose: Current research aimed to fabricate inclusion complexation of EPL ... -
Nano-Formulation Based Intravesical Drug Delivery Systems: An Overview of Versatile Approaches to Improve Urinary Bladder Diseases
Sarfraz, Muhammad; Qamar, Shaista; Rehman, Masood Ur; Tahir, Muhammad Azam; Ijaz, Muhammad; Ahsan, Anam; Asim, Mulazim Hussain; Nazir, Imran (MDPI, 2022)Intravesical drug delivery is a direct drug delivery approach for the treatment of various bladder diseases. The human urinary bladder has distinctive anatomy, making it an effective barrier against any toxic agent seeking ...