Browsing Pharmacy by Title
Now showing items 180-199 of 281
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The microbiome-product colibactin hits unique cellular targets mediating host–microbe interaction
(Frontiers Media S.A., 2022)The human microbiota produces molecules that are evolved to interact with the diverse cellular machinery of both the host and microbes, mediating health and diseases. One of the most puzzling microbiome molecules is ... -
Microfluidic-based nanoplatforms for cancer theranostic applications: A mini-review on recent advancements
(Elsevier Inc., 2024-01)Cancer is amongst the foremost causes of death worldwide, and the field of nanotechnology presents promising prospects in terms of diagnostic and therapeutic approaches. Theranostics are nanoparticles (NPs) that possess ... -
Mimosa pudica mucilage nanoparticles of losartan potassium: Characterization and pharmacodynamics evaluation
(Elsevier B.V., 2023)The current research was to develop nanoparticles based on Mimosa pudica mucilage (MPM) that could encapsulate losartan potassium (LP). Nanoparticles (NPs) produced through ionic-gelation method; the polymerization of the ... -
Mobile Phones: Reservoirs of Resistant Bacteria during the COVID-19 Pandemic in Abu Dhabi, United Arab Emirates
(MDPI, 2023)Background: Mobile phones are excessively used even though microbes’ ability to survive on phone surfaces was confirmed. During the COVID-19 pandemic, heavy hygiene practices have been applied to mobile surfaces. Therefore, ... -
Modulating the majority charge carrier type and performance of organic heterojunction ammonia sensors by increasing peripheral fluorination of the silicon phthalocyanine sublayer
(Elsevier B.V., 2024-06-01)Silicon phthalocyanines (R2-SiPcs) are an emerging class of high-performance organic semiconductors which have recently found application in highly sensitive and selective bilayer organic heterojunction devices for ammonia ... -
Molecular Modelling Study and Antibacterial Evaluation of Diphenylmethane Derivatives as Potential FabI Inhibitors
(MDPI, 2023)The need for new antibiotics has become a major worldwide challenge as bacterial strains keep developing resistance to the existing drugs at an alarming rate. Enoyl-acyl carrier protein reductases (FabI) play a crucial ... -
Motivators, Barriers, and Acceptance of COVID-19 Vaccination among Residents of Western Saudi Arabia
(MDPI, 2022)Background: There are limited studies that have assessed COVID-19 vaccine acceptance and side effects, both globally and in the western region of Saudi Arabia (SA). Objective: This study assessed the acceptance of vaccination ... -
Multi-Method Analysis of Histopathological Image for Early Diagnosis of Oral Squamous Cell Carcinoma Using Deep Learning and Hybrid Techniques
(Multidisciplinary Digital Publishing Institute (MDPI), 2023-11)Oral cancer is a fatal disease and ranks seventh among the most common cancers throughout the whole globe. Oral cancer is a type of cancer that usually affects the head and neck. The current gold standard for diagnosis is ... -
Mutaba'ah - Mother and Child Health Study: Protocol for a prospective cohort study investigating the maternal and early life determinants of infant, child, adolescent and maternal health in the United Arab Emirates
(BMJ Publishing Group., 2021)Introduction: Early life exposures, particularly environmental and parental lifestyle factors, have a major influence on children's health and development. Due to increasing interest in the early life developmental origins ... -
Nano-Formulation Based Intravesical Drug Delivery Systems: An Overview of Versatile Approaches to Improve Urinary Bladder Diseases
(MDPI, 2022)Intravesical drug delivery is a direct drug delivery approach for the treatment of various bladder diseases. The human urinary bladder has distinctive anatomy, making it an effective barrier against any toxic agent seeking ... -
Nano-sized droplets of self-emulsifying system for enhancing oral bioavailability of chemotherapeutic agent VP-16 in rats: A nano lipid carrier for BCS class IV drugs
(Canadian Society for Pharmaceutical Sciences., 2018)PURPOSE: The purpose of this study was to investigate the ability of a self-nano-emulsifying drug delivery system (SNEDDS) to enhance the oral bioavailability of a BCS class IV drug, etoposide (VP-16). METHOD: A series of ... -
Nanomedicines: Emerging Platforms in Smart Chemotherapy Treatment—A Recent Review
(Multidisciplinary Digital Publishing Institute (MDPI), 2024-03)Cancer continues to pose one of the most critical challenges in global healthcare. Despite the wide array of existing cancer drugs, the primary obstacle remains in selectively targeting and eliminating cancer cells while ... -
Nanoparticles in clinical trials of COVID-19: An update
(Elsevier Ltd, 2022)Once the World Health Organization (WHO) declared the COVID-19 (Coronavirus Infectious Disease-19) outbreak to be pandemic, massive efforts have been launched by researchers around the globe to combat this emerging infectious ... -
Nanosized liposomes containing bile salt: A vesicular nanocarrier for enhancing oral bioavailability of BCS class III drug
(Canadian Society for Pharmaceutical Sciences, 2017)PURPOSE: Liposomes have been studied as a colloidal carrier in drug delivery systems, especially for oral administration. However, their low structural integrity in the gut is still a major shortcoming. Membrane disruptive ... -
Nanostructured lipid carriers based suppository for enhanced rectal absorption of ondansetron: In vitro and in vivo evaluations
(Elsevier B.V., 2021)The current research aimed to fabricate ondansetron nanostructured lipid carriers (OND-NLCs) and incorporate them into a suppository base to manage chemotherapy-induced vomiting and nausea, which offer the advantage of ... -
Nanotechnology-Based Drug Delivery Approaches of Mangiferin: Promises, Reality and Challenges in Cancer Chemotherapy
(Multidisciplinary Digital Publishing Institute (MDPI), 2023)Mangiferin (MGF), a xanthone derived from Mangifera indica L., initially employed as a nutraceutical, is now being explored extensively for its anticancer potential. Scientists across the globe have explored this bioactive ... -
A narrative review of approved and emerging anti-obesity medications
(Elsevier B.V., 2023)Background: Recently, many drugs have been approved for halting overweight and obesity—few types of research shifted to using Anti-obesity medications (AOM) solely for well-being and shape-keeping. Objective: This narrative ... -
A new hydrophobic deep eutectic solvent composed of menthol and tris(2-ethylhexyl) phosphate for solvent bar microextraction of parabens from biological fluids
(KeAi Communications Co., 2024-06)Parabens are antimicrobial preservatives with extensive applications in cosmetics, toiletries, pharmaceuticals, and food. Considering the legitimate concerns relating to their potential to disrupt multiple endocrine ... -
New Insights Into the Anticonvulsant Effects of Essential Oil From Melissa officinalis L. (Lemon Balm)
(Frontiers Media S.A., 2021)Melissa officinalis L. is used in traditional European and Iranian folk medicines to treat a plethora of neurological diseases including epilepsy. We utilized the in vitro and in vivo models of epilepsy to probe the ... -
Non Pharmaceutical Interventions for Optimal Control of COVID-19
(Elsevier, 2020)Background and Objective: The outbreak of the current pandemic begun from the first individual of a 55-year old from Hubei province in China, the disease instigated by the new coronavirus spreading across the world. ...