Browsing Pharmaceutical Sciences by Subject "Lisinopril, PBPK, Pediatric, PK-Sim MoBI®, Area under the curve"
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Prediction of lisinopril pediatric dose from the reference adult dose by employing a physiologically based pharmacokinetic model
(BioMed Central, 2020)Background: This study aimed to assess the pediatric lisinopril doses using an adult physiological based pharmacokinetic (PBPK) model. As the empirical rules of dose calculation cannot calculate gender-specific pediatric ...