Browsing Pharmaceutical Sciences by Subject "Aggregation, Huntington's disease, Luteolin, misfolded protein, Neurodegenerative diseases"
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The flavonoid luteolin reduces mutant huntingtin aggregation and cytotoxicity in huntingtin-mutated neuroblastoma cells
(Elsevier B.V., 2023-12)Background: Huntington's disease is an inherited progressive neurodegenerative disorder caused by an expansion of the polyglutamine tract leading to malformation and aggregation of the mutant huntingtin protein in the cell ...