Browsing Pharmaceutical Sciences by Author "Sarfraz, Muhammad K."
Now showing items 1-5 of 5
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Butylglyceryl pectin nanoparticles: Synthesis, formulation and characterization
Bostanudin, Mohammad F.; Arafat, Mosab; Sarfraz, Muhammad K.; Gôrecki, Dariusz C.; Barbu, Eugen (MDPI AG., 2019)Pectin is a polysaccharide with very good gel forming properties that traditionally has found important applications in foods and pharmaceutical industries. Although less studied, chemical modifications of pectin leading ... -
A cross-sectional study on knowledge, attitude and practices of medical doctors towards antibiotic prescribing patterns and resistance in Khyber Pakhtun Khawah, Pakistan
Faizullah, Maira; Nisar-Ur-Rahman; Umar, Muhammad Ihtesham; Anwar, Mudassir; Sarfraz, Muhammad K. (Open Science Publishers LLP Inc., 2017)Irrational prescribing and resistance to antibiotics are major health concerns globally. The aim of this study was to assess the physicians' knowledge, attitude and practice about antibiotic prescribing and resistance in ... -
Nano-sized droplets of self-emulsifying system for enhancing oral bioavailability of chemotherapeutic agent VP-16 in rats: A nano lipid carrier for BCS class IV drugs
Khalid, Nayab; Sarfraz, Muhammad K.; Arafat, Mosab; Akhtar, Muhammad; Löbenberg, Raimar; Nisar-Ur-Rahman (Canadian Society for Pharmaceutical Sciences., 2018)PURPOSE: The purpose of this study was to investigate the ability of a self-nano-emulsifying drug delivery system (SNEDDS) to enhance the oral bioavailability of a BCS class IV drug, etoposide (VP-16). METHOD: A series of ... -
Nanosized liposomes containing bile salt: A vesicular nanocarrier for enhancing oral bioavailability of BCS class III drug
Arafat, Mosab; Kirchhoefer, Cathrin; Mikov, Momir M.; Sarfraz, Muhammad K.; Löbenberg, Raimar (Canadian Society for Pharmaceutical Sciences, 2017)PURPOSE: Liposomes have been studied as a colloidal carrier in drug delivery systems, especially for oral administration. However, their low structural integrity in the gut is still a major shortcoming. Membrane disruptive ... -
Transdermal patches: Design and current approaches to painless drug delivery
Al-Hanbali, Othman A.R.; Khan, Hajji Muhammad Shoaib; Sarfraz, Muhammad K.; Arafat, Mosab; Ijaz, Shakeel; Hameed, Abdul (Sciendo, 2019)Use of transdermal patches can evade many issues associated with oral drug delivery, such as first-pass hepatic metabolism, enzymatic digestion attack, drug hydrolysis and degradation in acidic media, drug fluctuations, ...