Browsing Pharmaceutical Sciences by Author "Minhas, Muhammad Usman"
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Biofunctional Hyaluronic Acid/κ-Carrageenan InjectableHydrogels for Improved Drug Delivery and Wound Healing
Ijaz, Uzma; Sohail, Muhammad; Minhas, Muhammad Usman; Khan, Shahzeb; Hussain, Zahid; Kazi, Mohsin; Shah, Syed Ahmed; Mahmood, Arshad; Maniruzzaman, Mohammed (MDPI, 2022)The in situ injectable hydrogel system offers a widespread range of biomedical applications in prompt chronic wound treatment and management, as it provides self-healing, maintains a moist wound microenvironment, and offers ... -
Carbopol Based Hydrogels for ITOPRIDE Hydrochloride Delivery; Synthesis, Characterization and Comparative Assessment with Various Monomers
Sarfraz, Muhammad; Iqbal, Rabia; Khan, Kifayat Ullah; Minhas, Muhammad Usman (MDPI, 2022)The objective of the current study was to synthesize and characterize carbopol containing hydrogels with different monomers such as methacrylic acid (MAA), 2-acrylamido-2-methylpropane sulfonic acid (AMPS) and itaconic ... -
Highly Responsive Chitosan-Co-Poly (MAA) Nanomatrices through Cross-Linking Polymerization for Solubility Improvement
Saleem, Anam; Akhtar, Naveed; Minhas, Muhammad Usman; Mahmood, Arshad; Ullah Khan, Kifayat; Abdullah, Orva (MDPI, 2022)In this study, we report the highly responsive chitosan-based chemically cross-linked nanomatrices, a nano-version of hydrogels developed through modified polymerization reaction for solubility improvement of poorly soluble ... -
Polyvinylpyrrolidone K-30-Based Crosslinked Fast Swelling Nanogels: An Impeccable Approach for Drug's Solubility Improvement
Minhas, Muhammad Usman; Khan, Kifayat Ullah; Sarfraz, Muhammad; Badshah, Syed Faisal; Munir, Abubakar; Barkat, Kashif; Basit, Abdul; Arafat, Mosab (NLM (Medline), 2022)Poor solubility is a global issue of copious pharmaceutical industries as large number of drugs in development stage as well as already marketed products are poorly soluble which results in low dissolution and ultimately ... -
Synthesis and Characterization of Carboxymethyl Chitosan Nanosponges with Cyclodextrin Blends for Drug Solubility Improvement
Rizvi, Syeda Sadia Batool; Akhtar, Naveed; Minhas, Muhammad Usman; Mahmood, Arshad; Khan, Kifayat Ullah (MDPI, 2022)This study aimed to enhance the solubility and release characteristics of docetaxel by synthesizing highly porous and stimuli responsive nanosponges, a nano-version of hydrogels with the additional qualities of both hydrogels ... -
Synthesis and Evaluation of Finasteride-Loaded HPMC-Based Nanogels for Transdermal Delivery: A Versatile Nanoscopic Platform
Ahmad, Aousaf; Ahmad, Mahmood; Minhas, Muhammad Usman; Sarfraz, Muhammad; Sohail, Muhammad; Khan, Kifayat Ullah; Tanveer, Sana; Ijaz, Shakeel (NLM (Medline), 2022)Herein, we report nanogels comprising diverse feed ratio of polymer hydroxypropyl methylcellulose (HPMC), monomer acrylic acid (AA), and cross-linker methylene bisacrylamide (MBA) fabricated for transdermal delivery of ...