Browsing Pharmaceutical Sciences by Author "Ghemrawi, Rose"
Now showing items 1-3 of 3
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Effects of subcutaneous vs. oral nanoparticle-mediated insulin delivery on hemostasis disorders in type 1 diabetes: A rat model study
Kaddour, Nawel; Benyettou, Farah; Moulai, Kawtar; Mebarki, Abdelouahab; Allal-Taouli, Katia; Ghemrawi, Rose; Whelan, Jamie; Merzouk, Hafida; Trabolsi, Ali; Mokhtari-Soulimane, Nassima Amel (Elsevier Ltd, 2024)Complications associated with Type 1 diabetes (T1D) have complex origins that revolve around chronic hyperglycemia; these complications involve hemostasis disorders, coagulopathies, and vascular damage. Our study aims to ... -
Endoplasmic reticulum stress and unfolded protein response in neurodegenerative diseases
Ghemrawi, Rose; Khair, Mostafa (MDPI AG., 2020)The endoplasmic reticulum (ER) is an important organelle involved in protein quality control and cellular homeostasis. The accumulation of unfolded proteins leads to an ER stress, followed by an adaptive response via the ... -
Molecular Modelling Study and Antibacterial Evaluation of Diphenylmethane Derivatives as Potential FabI Inhibitors
Hasan, Shaima; Kayed, Kawthar; Ghemrawi, Rose; Bataineh, Nezar Al; Mahgoub, Radwa E.; Audeh, Rola; Aldulaymi, Raghad; Atatreh, Noor; Ghattas, Mohammad A. (MDPI, 2023)The need for new antibiotics has become a major worldwide challenge as bacterial strains keep developing resistance to the existing drugs at an alarming rate. Enoyl-acyl carrier protein reductases (FabI) play a crucial ...