Now showing items 1-12 of 12

    • Berberine as a Potential Anticancer Agent:A Comprehensive Review 

      Rauf, Abdur; Abu-Izneid, Tareq; Khalil, Anees Ahmed; Imran, Muhammad; Shah, Zafar Ali; Emran, Talha Bin; Mitra, Saikat; Khan, Zidan; Alhumaydhi, Fahad A.; Aljohani, Abdullah S. M.; Khan, Ishaq; Rahman, Md. Mominur; Jeandet, Philippe; Gondal, Tanweer Aslam (MDPI, 2021)
      Berberine (BBR), a potential bioactive agent, has remarkable health benefits. A substantial amount of research has been conducted to date to establish the anticancer potential of BBR. The present review consolidates salient ...
    • COVID-19 Pandemic: Epidemiology, Etiology, Conventional and Non-Conventional Therapies 

      Rauf, Abdur; Abu-Izneid, Tareq; Olatunde, Ahmed; Khalil, Anees Ahmed; Alhumaydhi, Fahad A.; Tufail, Tabussam; Shariati, Mohammad Ali; Rebezov, Maksim; Almarhoon, Zainab M.; Mabkhot, Yahia N.; Alsayari, Abdulrhman; Rengasamy, Kannan R. R. (MDPI, 2020)
      Coronavirus disease 2019 (COVID-19), which reported in an outbreak in 2019 in Wuhan, Hubei province, China, is caused by the SARS-CoV-2 virus. The virus belongs to the beta-coronavirus class, along with the Middle East ...
    • Current advances of functional phytochemicals in Nicotiana plant and related potential value of tobacco processing waste: A review 

      Zou, Xinda; BK, Amrit; Abu-Izneid, Tareq; Aziz, Ahsan; Devnath, Popy; Rauf, Abdur; Mitra, Saikat; Emran, Talha Bin; Mujawah, Adil A.H.; Lorenzo, Jose M.; Mubarak, Mohammad S.; Wilairatana, Polrat; Suleria, HafizA.R. (Elsevier Masson s.r.l., 2021)
      Tobacco is grown in large quantities worldwide as a widely distributed commercial crop. From the harvest of the field to the process into the final product, a series of procedures generate enormous amount of waste materials ...
    • Density functional theory (DFT), molecular docking, and xanthine oxidase inhibitory studies of dinaphthodiospyrol S from Diospyros kaki L 

      Abu-Izneid, Tareq; Rauf, Abdur; Ahmad, Zubair; Wadood, Abdul; Ayub, Khurshid; Muhammad, Naveed; Al-Awthan, Yahya S.; Maqbool, Maria; Bahattab, Omar S.; Hemeg, Hassan A.; Naz, Saima; Formanowicz, Dorota (Elsevier B.V., 2024-02)
      In this work, we investigated Diospyros kaki extract and an isolated compound for their potential as xanthine oxidase (XO) inhibitors, a target enzyme involved in inflammatory disorders. The prepared extract was subjected ...
    • Discovery of new α-glucosides, antiglycation agent, and in silico study of 2-(3,4-dihydroxyphenyl)-7,8-dihydroxy-3-methoxy-4H-chromen-4-one isolated from Pistacia chinensis 

      Abu-Izneid, Tareq; Rauf, Abdur; Akram, Zuneera; Naz, Saima; Wadood, Abdul; Muhammad, Naveed; Hayat, Chandni; Al-Awthan, Yahya S.; Bahattab, Omar S. (Elsevier Ltd, 2024-03-15)
      Pistacia chinensis is locally practiced for treating diabetes, pain, inflammation, and erectile dysfunction. Therefore, the current studies subjected the crude extract/fractions and the isolated compound (2-(3,4-dihydrox ...
    • Estimation of dihydroartemisinin in human plasma using a highly sensitive LTQ Orbitrap mass spectrometer with Xcalibur software 

      Abu-Izneid, Tareq; Abbas, Muhammad; Watson, David G.; Shah, Yasar; Shah, Sayyed I.; Khuda, Fazli (Frontiers Media S.A., 2023)
      Background: Artemether (ARM), the O-methyl ether prodrug of dihydroartemisinin (DHA), is considered a first-line antimalarial agent. Artemether is extensively metabolized in vivo to its active metabolite DHA, and therefore ...
    • How to face COVID-19: proposed treatments based on remdesivir and hydroxychloroquine in the presence of zinc sulfate. Docking/DFT/POM structural analysis 

      Ben Hadda, Taibi; Berredjem, Malika; Almalki, Faisal A.; Rastija, Vesna; Jamalis, Joazaizulfazli; Bin Emran, Talha; Abu-Izneid, Tareq; Esharkawy, Eman; Rodriguez, Luis Cruz; Alqahtani, Ali M. (Taylor and Francis Ltd., 2021)
      Remdesivir and hydroxychloroquine derivatives form two important classes of heterocyclic compounds. They are known for their anti-malarial biological activity. This research aims to analyze the physicochemical properties ...
    • Immune system response during viral Infections: Immunomodulators, cytokine storm (CS) and Immunotherapeutics in COVID-19 

      Pottoo, Faheem Hyder; Abu-Izneid, Tareq; Ibrahim, Abdallah Mohammad; Javed, Md. Noushad; AlHajri, Noora; Hamroun, Amar M. (Elsevier B.V., 2021)
      Coronaviruses are non-segmented and single stranded positive-sense RNA (+ssRNA) viruses. To date, 06 human coronaviruses (HCoVs) are reported; α-CoVs (HCoVs-NL63 and HCoVs-229E) and β-CoVs (HCoVs-OC43, HCoVs-HKU1, SARS-CoV, ...
    • Micro-RNAs in the regulation of immune response against SARS CoV-2 and other viral infections 

      Abu-Izneid, Tareq; AlHajri, Noora; Ibrahim, Abdallah Mohammad; Javed, Md. Noushad; Salem, Khairi Mustafa; Pottoo, Faheem Hyder; Kamal, Mohammad Amjad (Elsevier B.V., 2021)
      Background: Micro-RNAs (miRNAS) are non-coding, small RNAs that have essential roles in different biological processes through silencing genes, they consist of 18–24 nucleotide length RNA molecules. Recently, miRNAs have ...
    • Nanoparticles in clinical trials of COVID-19: An update 

      Rauf, Abdur; Abu-Izneid, Tareq; Khalil, Anees Ahmed; Hafeez, Nabia; Olatunde, Ahmed; Rahman, Mominur; Semwal, Prabhakar; Al-Awthan, Yahya Saleh; Bahattab, Omar Salem; Khan, Ishaq N.; Khan, Muhammad Arslan; Sharma, Rohit (Elsevier Ltd, 2022)
      Once the World Health Organization (WHO) declared the COVID-19 (Coronavirus Infectious Disease-19) outbreak to be pandemic, massive efforts have been launched by researchers around the globe to combat this emerging infectious ...
    • The pharmacological basis of Cuscuta reflexa whole plant as an antiemetic agent in pigeons 

      Muhammad, Naveed; Ullah, Sana; Abu-Izneid, Tareq; Rauf, Abdur; Shehzad, Omer; Atif, Muhammad; Khan, Haroon; Naz, Humira; Herrera-Calderon, Oscar; Khalil, Anees Ahmed; Sahab Uddin, Md. (Elsevier Inc., 2020)
      Cuscuta reflexa has been traditionally used as an antiemetic. Additionally, it has been used in various herbal formulations for the treatment of emesis. So far, there is no scientific evidence of the plant extract as ...
    • Sedative, muscle relaxant-like effects, and molecular docking study of compounds isolated from salvia leriifolia 

      Hussain, Amjad; Rauf, Abdur; Abu-Izneid, Tareq; Ibrahim, Muhammad; Abrar, Shazia; Khan, Haroon; Ullah, Barkath; Cerón-Carrasco, José Pedro; Pérez-Sánchez, Horacio; Choudhary, Muhammad Iqbal; Mubarak, Mohammad S.; Shariati, Mohammad Ali; Mabkhot, Yahia N.; Bourguet-Kondracki, Marie-Lise (Springer Science and Business Media Deutschland GmbH, 2020)
      Salvia leriifolia Benth., Lamiaceae, an endemic medicinal plant of the northern region of Iran, has been documented as sedative. It has been used in traditional medicine for its muscle relaxation effect. The need for ...