Browsing by Author "Akhtar, Muhammad"
Now showing items 1-2 of 2
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Enhanced Oral Bioavailability of Epalrestat SBE7-β-CD Complex Loaded Chitosan Nanoparticles: Preparation, Characterization and in-vivo Pharmacokinetic Evaluation
Alvi, Zunaira; Akhtar, Muhammad; Mahmood, Arshad; Ur-Rahman, Nisar; Nazir, Imran; Sadaquat, Hadia; Ijaz, Muhammad; Syed, Shahzada Khurram; Waqas, Muhammad Khurram; Wang, Yi (NLM (Medline), 2021)Background: Epalrestat (EPL) is a carboxylic acid derivative with poor aqueous solubility and its pharmacokinetic features are not fully defined. Purpose: Current research aimed to fabricate inclusion complexation of EPL ... -
Nano-sized droplets of self-emulsifying system for enhancing oral bioavailability of chemotherapeutic agent VP-16 in rats: A nano lipid carrier for BCS class IV drugs
Khalid, Nayab; Sarfraz, Muhammad K.; Arafat, Mosab; Akhtar, Muhammad; Löbenberg, Raimar; Nisar-Ur-Rahman (Canadian Society for Pharmaceutical Sciences., 2018)PURPOSE: The purpose of this study was to investigate the ability of a self-nano-emulsifying drug delivery system (SNEDDS) to enhance the oral bioavailability of a BCS class IV drug, etoposide (VP-16). METHOD: A series of ...