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Controlled release of pyrimidine compound using polymeric coated ZIF-8 metal-organic framework as glucagon-like peptide-1 receptor agonist carrier

AlNeyadi, Shaikha S.; Amir, Naheed; Ghattas, Mohammad A.; Atatreh, Noor; Alketbi, Shaikha S.; Al Ajeil, Ruba; Adem, Abdu (MDPI AG., 2020)

This work demonstrates synthetic strategies for the incorporation of a synthesized pyrimidine glucagon-like peptide-1 (GLP-1) agonist into alginate-coated ZIF-8. The prepared pyrimidine GLP-1 agonist used for the treatment ...