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Micro-RNAs in the regulation of immune response against SARS CoV-2 and other viral infections
(Elsevier B.V., 2021)
Background: Micro-RNAs (miRNAS) are non-coding, small RNAs that have essential roles in different biological processes through silencing genes, they consist of 18–24 nucleotide length RNA molecules. Recently, miRNAs have ...
Immune system response during viral Infections: Immunomodulators, cytokine storm (CS) and Immunotherapeutics in COVID-19
(Elsevier B.V., 2021)
Coronaviruses are non-segmented and single stranded positive-sense RNA (+ssRNA) viruses. To date, 06 human coronaviruses (HCoVs) are reported; α-CoVs (HCoVs-NL63 and HCoVs-229E) and β-CoVs (HCoVs-OC43, HCoVs-HKU1, SARS-CoV, ...
In vivo analgesic, anti-inflammatory, and sedative activity and a molecular docking study of dinaphthodiospyrol g isolated from diospyros lotus
(BioMed Central Ltd., 2020)
Background: Analgesic, anti-inflammatory, and sedative drugs are available with potential side effects such as peptic ulcer and addiction among other things. In this regard, research is underway to find safe, effective, ...
The pharmacological basis of Cuscuta reflexa whole plant as an antiemetic agent in pigeons
(Elsevier Inc., 2020)
Cuscuta reflexa has been traditionally used as an antiemetic. Additionally, it has been used in various herbal formulations for the treatment of emesis. So far, there is no scientific evidence of the plant extract as ...
Sedative, muscle relaxant-like effects, and molecular docking study of compounds isolated from salvia leriifolia
(Springer Science and Business Media Deutschland GmbH, 2020)
Salvia leriifolia Benth., Lamiaceae, an endemic medicinal plant of the northern region of Iran, has been documented as sedative. It has been used in traditional medicine for its muscle relaxation effect. The need for ...
How to face COVID-19: proposed treatments based on remdesivir and hydroxychloroquine in the presence of zinc sulfate. Docking/DFT/POM structural analysis
(Taylor and Francis Ltd., 2021)
Remdesivir and hydroxychloroquine derivatives form two important classes of heterocyclic compounds. They are known for their anti-malarial biological activity. This research aims to analyze the physicochemical properties ...
COVID-19 Pandemic: Epidemiology, Etiology, Conventional and Non-Conventional Therapies
(MDPI, 2020)
Coronavirus disease 2019 (COVID-19), which reported in an outbreak in 2019 in Wuhan, Hubei province, China, is caused by the SARS-CoV-2 virus. The virus belongs to the beta-coronavirus class, along with the Middle East ...
Current advances of functional phytochemicals in Nicotiana plant and related potential value of tobacco processing waste: A review
(Elsevier Masson s.r.l., 2021)
Tobacco is grown in large quantities worldwide as a widely distributed commercial crop. From the harvest of the field to the process into the final product, a series of procedures generate enormous amount of waste materials ...
Berberine as a Potential Anticancer Agent:A Comprehensive Review
(MDPI, 2021)
Berberine (BBR), a potential bioactive agent, has remarkable health benefits. A substantial amount of research has been conducted to date to establish the anticancer potential of BBR. The present review consolidates salient ...
Nanoparticles in clinical trials of COVID-19: An update
(Elsevier Ltd, 2022)
Once the World Health Organization (WHO) declared the COVID-19 (Coronavirus Infectious Disease-19) outbreak to be pandemic, massive efforts have been launched by researchers around the globe to combat this emerging infectious ...