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Biofunctional Hyaluronic Acid/κ-Carrageenan InjectableHydrogels for Improved Drug Delivery and Wound Healing

Ijaz, Uzma; Sohail, Muhammad; Minhas, Muhammad Usman; Khan, Shahzeb; Hussain, Zahid; Kazi, Mohsin; Shah, Syed Ahmed; Mahmood, Arshad; Maniruzzaman, Mohammed (MDPI, 2022)

The in situ injectable hydrogel system offers a widespread range of biomedical applications in prompt chronic wound treatment and management, as it provides self-healing, maintains a moist wound microenvironment, and offers ...

Synthesis and Characterization of Carboxymethyl Chitosan Nanosponges with Cyclodextrin Blends for Drug Solubility Improvement

Rizvi, Syeda Sadia Batool; Akhtar, Naveed; Minhas, Muhammad Usman; Mahmood, Arshad; Khan, Kifayat Ullah (MDPI, 2022)

This study aimed to enhance the solubility and release characteristics of docetaxel by synthesizing highly porous and stimuli responsive nanosponges, a nano-version of hydrogels with the additional qualities of both hydrogels ...

Formulation and evaluation of quince seeds mucilage – sodium alginate microspheres for sustained delivery of cefixime and its toxicological studies

Ghumman, Shazia Akram; Mahmood, Arshad; Noreen, Sobia; Rana, Mavra; Hameed, Huma; Ijaz, Bushra; Hasan, Sara; Aslam, Afeefa; Fayyaz ur Rehman, Muhammad (Elsevier B.V., 2022)

Quince seed mucilage was used in a combination of sodium alginate to develop sustained-release microspheres of cefixime. Physical characterizations such as FTIR, TGA, DSC, and SEM were performed on the prepared microspheres. ...

Preliminary Investigation of Linum usitatissimum Mucilage-Based Hydrogel as Possible Substitute to Synthetic Polymer-Based Hydrogels for Sustained Release Oral Drug Delivery

Mahmood, Arshad; Erum, Alia; Mumtaz, Sophia; Tulain, Ume Ruqia; Malik, Nadia Shamshad; Alqahtani, Mohammed S. (MDPI, 2022)

The aim of this study was to investigate the potential of Linum usitatissimum mucilage, a natural polymer, in developing a sustained release hydrogel for orally delivered drugs that require fre-quent dosing. For this ...

Highly Responsive Chitosan-Co-Poly (MAA) Nanomatrices through Cross-Linking Polymerization for Solubility Improvement

Saleem, Anam; Akhtar, Naveed; Minhas, Muhammad Usman; Mahmood, Arshad; Ullah Khan, Kifayat; Abdullah, Orva (MDPI, 2022)

In this study, we report the highly responsive chitosan-based chemically cross-linked nanomatrices, a nano-version of hydrogels developed through modified polymerization reaction for solubility improvement of poorly soluble ...

Papain-Decorated Mucopenetrating SEDDS: A Tentative Approach to Combat Absorption Issues of Acyclovir via the Oral Route

Mahmood, Arshad; Haneef, Rabbia; Al Meslamani, Ahmad Z.; Bostanudin, Mohammad F.; Sohail, Muhammad; Sarfraz, Muhammad; Arafat, Mosab (MDPI, 2022)

The aim of the current study was to enhance the oral bioavailability of Acyclovir (ACV) based on the papain-functionalized self-emulsifying drug delivery systems (SEDDS). The optimum control SEDDS formulation comprised of ...