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Cortisol and breast cancer: A review of clinical and molecular evidence
(PJD Publications Ltd., 2018)
Breast cancer (BC) is a commonly diagnosed cancer amongst women and the second leading cause of cancer deaths in the world. BC has created huge challenges to healthcare providers regarding the identification of main risk ...
Causality and preventability assessment of adverse drug reactions and adverse drug events of antibiotics among hospitalized patients: A multicenter, cross-sectional study in Lahore, Pakistan
(Public Library of Science, 2018)
Background and objectives Adverse drug events (ADEs) are the fifth leading cause of death and thus responsible for a large number of hospital admissions in all over the globe. This study was aimed to assess the antibiotics ...
Causality and preventability assessment of adverse drug events of antibiotics among inpatients having different lengths of hospital stay: A multicenter, cross-sectional study in Lahore, Pakistan
(BioMed Central Ltd., 2018)
Background: A large number of hospital admissions are attributed to adverse drug reactions (ADRs) and they are the fifth leading cause of death worldwide. The present study aimed to assess the causality and preventability ...
Comparison of the application of treatment Panel III and American College of Cardiology/American heart Association guidelines for blood cholesterol treatment in Saudi Arabia
(Elsevier B.V., 2018)
Background: One of the major risk factors for cardiovascular diseases is hyperlipidemia. The primary aim of this study was to estimate the proportion of individuals between 40–75 years old that would be eligible for statin ...
Current enlightenment about etiology and pharmacological treatment of autism spectrum disorder
(Frontiers Media S.A., 2018)
Autistic Spectrum Disorder (ASD) is a complex neurodevelopmental brain disorder characterized by two core behavioral symptoms, namely impairments in social communication and restricted/repetitive behavior. The molecular ...
Influence of education level of older patients on polypharmacy, potentially inappropriate medications listed in Beer’s criteria, and unplanned hospitalization: A cross-sectional study in Lahore, Pakistan
(MDPI AG., 2018)
Objective: To evaluate influence of education level of older patients on polypharmacy, potentially inappropriate medications (PIMs) listed in Beer’s Criteria, and unplanned hospitalization. Methods: A cross-sectional study ...
Evaluating quantity and quality of literature focusing on health economics and pharmacoeconomics in Gulf Cooperation Council countries
(Taylor and Francis Ltd., 2018)
Background: The importance of pharmacoeconomics and health economics has been augmented. It has the potential to provide evidence to aid in optimal decision-making in the funding of cost-effective medicines and services ...
Nano-sized droplets of self-emulsifying system for enhancing oral bioavailability of chemotherapeutic agent VP-16 in rats: A nano lipid carrier for BCS class IV drugs
(Canadian Society for Pharmaceutical Sciences., 2018)
PURPOSE: The purpose of this study was to investigate the ability of a self-nano-emulsifying drug delivery system (SNEDDS) to enhance the oral bioavailability of a BCS class IV drug, etoposide (VP-16). METHOD: A series of ...
Safety Assessment of Neoadjuvant Pertuzumab Combined with Trastuzumab in Nonmetastatic HER2-Positive Breast Cancer in Postmenopausal Elderly Women of South Asia
(Hindawi Limited, 2018)
Aim: To evaluate the safety issues and adverse effects of using TCHP regimen (docetaxel, carboplatin, trastuzumab, and pertuzumab) versus TCP regimen (docetaxel, carboplatin, and trastuzumab) in older postmenopausal women ...
Kinetics of oxidation of atropine by K2Cr2O7 in acidic aqueous solutions
(Chemical Publishing Co., 2018)
Oxidation of atropine (ATN) by K2Cr2O7 has been studied kinetically in aqueous strongly acidic solutions. The kinetics of this reaction was investigated at different temperatures. A constant pH and constant ionic strength ...