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Development of Niacinamide/Ferulic Acid-Loaded Multiple Emulsion and Its In Vitro/In Vivo Investigation as a Cosmeceutical Product

Huma, Sidra; Khan, Haji Muhammad Shoaib; Ijaz, Shakeel; Sarfraz, Muhammad; Zaka, Hafiz Saqib; Ahmad, Aousaf (NLM (Medline), 2022)

Objective: Multiple emulsions have the ability to incorporate both lipophilic and hydrophilic actives in the same preparation and facilitate permeation of active ingredients through skin. The current study was aimed at ...

Synthesis and Evaluation of Finasteride-Loaded HPMC-Based Nanogels for Transdermal Delivery: A Versatile Nanoscopic Platform

Ahmad, Aousaf; Ahmad, Mahmood; Minhas, Muhammad Usman; Sarfraz, Muhammad; Sohail, Muhammad; Khan, Kifayat Ullah; Tanveer, Sana; Ijaz, Shakeel (NLM (Medline), 2022)

Herein, we report nanogels comprising diverse feed ratio of polymer hydroxypropyl methylcellulose (HPMC), monomer acrylic acid (AA), and cross-linker methylene bisacrylamide (MBA) fabricated for transdermal delivery of ...

Polyvinylpyrrolidone K-30-Based Crosslinked Fast Swelling Nanogels: An Impeccable Approach for Drug's Solubility Improvement

Minhas, Muhammad Usman; Khan, Kifayat Ullah; Sarfraz, Muhammad; Badshah, Syed Faisal; Munir, Abubakar; Barkat, Kashif; Basit, Abdul; Arafat, Mosab (NLM (Medline), 2022)

Poor solubility is a global issue of copious pharmaceutical industries as large number of drugs in development stage as well as already marketed products are poorly soluble which results in low dissolution and ultimately ...

Papain-Decorated Mucopenetrating SEDDS: A Tentative Approach to Combat Absorption Issues of Acyclovir via the Oral Route

Mahmood, Arshad; Haneef, Rabbia; Al Meslamani, Ahmad Z.; Bostanudin, Mohammad F.; Sohail, Muhammad; Sarfraz, Muhammad; Arafat, Mosab (MDPI, 2022)

The aim of the current study was to enhance the oral bioavailability of Acyclovir (ACV) based on the papain-functionalized self-emulsifying drug delivery systems (SEDDS). The optimum control SEDDS formulation comprised of ...

Nano-Formulation Based Intravesical Drug Delivery Systems: An Overview of Versatile Approaches to Improve Urinary Bladder Diseases

Sarfraz, Muhammad; Qamar, Shaista; Rehman, Masood Ur; Tahir, Muhammad Azam; Ijaz, Muhammad; Ahsan, Anam; Asim, Mulazim Hussain; Nazir, Imran (MDPI, 2022)

Intravesical drug delivery is a direct drug delivery approach for the treatment of various bladder diseases. The human urinary bladder has distinctive anatomy, making it an effective barrier against any toxic agent seeking ...

Carbopol Based Hydrogels for ITOPRIDE Hydrochloride Delivery; Synthesis, Characterization and Comparative Assessment with Various Monomers

Sarfraz, Muhammad; Iqbal, Rabia; Khan, Kifayat Ullah; Minhas, Muhammad Usman (MDPI, 2022)

The objective of the current study was to synthesize and characterize carbopol containing hydrogels with different monomers such as methacrylic acid (MAA), 2-acrylamido-2-methylpropane sulfonic acid (AMPS) and itaconic ...