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Synthesis and Evaluation of Finasteride-Loaded HPMC-Based Nanogels for Transdermal Delivery: A Versatile Nanoscopic Platform

Ahmad, Aousaf; Ahmad, Mahmood; Minhas, Muhammad Usman; Sarfraz, Muhammad; Sohail, Muhammad; Khan, Kifayat Ullah; Tanveer, Sana; Ijaz, Shakeel (NLM (Medline), 2022)

Herein, we report nanogels comprising diverse feed ratio of polymer hydroxypropyl methylcellulose (HPMC), monomer acrylic acid (AA), and cross-linker methylene bisacrylamide (MBA) fabricated for transdermal delivery of ...

Polyvinylpyrrolidone K-30-Based Crosslinked Fast Swelling Nanogels: An Impeccable Approach for Drug's Solubility Improvement

Minhas, Muhammad Usman; Khan, Kifayat Ullah; Sarfraz, Muhammad; Badshah, Syed Faisal; Munir, Abubakar; Barkat, Kashif; Basit, Abdul; Arafat, Mosab (NLM (Medline), 2022)

Poor solubility is a global issue of copious pharmaceutical industries as large number of drugs in development stage as well as already marketed products are poorly soluble which results in low dissolution and ultimately ...

Carbopol Based Hydrogels for ITOPRIDE Hydrochloride Delivery; Synthesis, Characterization and Comparative Assessment with Various Monomers

Sarfraz, Muhammad; Iqbal, Rabia; Khan, Kifayat Ullah; Minhas, Muhammad Usman (MDPI, 2022)

The objective of the current study was to synthesize and characterize carbopol containing hydrogels with different monomers such as methacrylic acid (MAA), 2-acrylamido-2-methylpropane sulfonic acid (AMPS) and itaconic ...

Evaluating the Aphrodisiac Potential of Mirabilis jalapa L. Root Extract: Phytochemical Profiling and In Silico, In Vitro, and In Vivo Assessments in Normal Male Rats

Rahman, Asad Ur; Alam, Fiaz; Khan, Muhammad; Sarfraz, Muhammad; Basit, Abdul; Ahmad, Tawseef; Khokhar, Muhammad Ali; Ali, Sayyad; Khan, Kifayat Ullah (Multidisciplinary Digital Publishing Institute (MDPI), 2023)

The traditional use of Mirabilis jalapa L. roots to enhance male sexual performance prompted us to assess the in silico, in vitro, and in vivo aphrodisiac activities of its hydroethanolic extract using normal male rats. ...

Fabrication, organoleptic evaluation and in vitro characterization of cream loaded with Carica papaya seed extract

Sarfraz, Muhammad; Shabbir, Kanwal; Adnan, Qazi; Khan, Haji Muhammad Shoaib; Shirazi, Jafir Hussain; Sabir, Hamna; Mehmood, Nimrah; Bin Jardan, Yousef A.; Khan, Kifayat Ullah; Basit, Abdul (John Wiley and Sons Inc, 2023)

Objective: The current study aimed to provide preliminary insights into potential biopharmaceutical applications of Carica papaya seed extract by evaluating its phytochemical and biological profiles. Furthermore, the study ...