Survivin is an inhibitor of apoptosis as well as a promoter of cell proliferation. Fibulin-3 is a matrix glycoprotein that displays potential for tumor suppression or propagation. The present study aimed to validate the ...

Background and Objective: Alzheimer's disease (AD) is a progressive neurodegenerative disease where symptoms appear after significant neuronal loss. Current treatments for AD do not significantly alter the disease process, ...

Butyrylcholinesterase (BChE) plays an important role in the progression of the Alzheimer’s disease. In this study, we used a structure-based virtual screening (VS) approach to discover new BChE inhibitors. A ligand database ...

Background and Objective: The dried tuber of Bongardia chrysogonum (L.) is a popular folk remedy for its use in the treatment of epilepsy in traditional medicine. The study aimed to evaluate the anti-oxidant and anti-convulsant ...

Osteoarthritis (OA) is a multifactorial disease that commonly affects the knee. Tumor Necrosis Factor-α (TNF-α) regulates inflammation during OA. Macrophage Migration Inhibitory Factor (MIF) may be involved in the ...

The leaves of Aloysia citriodora Palau (Jordanian “malliseh”) are traditionally used to remediate irritative gastrointestinal symptoms. The aim of this study is to assess the spasmolytic activity of the ethanolic extract ...

Peganum harmala L., Zygophyllaceae popularly known as Wild Syrian rue, a well-known plant in folk medicine for many pharmacological uses including antispasmodic activity. Chemical composition of the plant showed that the ...

Introduction: Understanding why adults resort to herbal medicine can help in planning interventions aimed at increasing awareness regarding herbal use. This study sought to investigate the prevalence and to determine factors ...

Purpose: Gephyrin (GPHN) is an essential protein in the regulation of inhibitory postsy-naptic density and polymorphism in the corresponding gene may have a role in the development of pharmacoresistant epilepsy (PRE). For ...

Luteolin is a naturally occurring secondary metabolite belonging to the class of flavones. As many other natural flavonoids, it is often found in combination with glycosides in many fruits, vegetables, and plants, contributing ...