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Nano Methotrexate versus Methotrexate in Targeting Rheumatoid Arthritis
(MDPI, 2023)Nanomedicine has emerged as an important approach for targeting RA medication. Rheumatoid arthritis (RA) is a widespread autoimmune disorder marked by multiple inflamed joints. Gold nanoparticles (GNPs) have been demonstrated ... -
Nano-Formulation Based Intravesical Drug Delivery Systems: An Overview of Versatile Approaches to Improve Urinary Bladder Diseases
(MDPI, 2022)Intravesical drug delivery is a direct drug delivery approach for the treatment of various bladder diseases. The human urinary bladder has distinctive anatomy, making it an effective barrier against any toxic agent seeking ... -
Nano-sized droplets of self-emulsifying system for enhancing oral bioavailability of chemotherapeutic agent VP-16 in rats: A nano lipid carrier for BCS class IV drugs
(Canadian Society for Pharmaceutical Sciences., 2018)PURPOSE: The purpose of this study was to investigate the ability of a self-nano-emulsifying drug delivery system (SNEDDS) to enhance the oral bioavailability of a BCS class IV drug, etoposide (VP-16). METHOD: A series of ... -
Nanoparticles in clinical trials of COVID-19: An update
(Elsevier Ltd, 2022)Once the World Health Organization (WHO) declared the COVID-19 (Coronavirus Infectious Disease-19) outbreak to be pandemic, massive efforts have been launched by researchers around the globe to combat this emerging infectious ... -
Nanosized liposomes containing bile salt: A vesicular nanocarrier for enhancing oral bioavailability of BCS class III drug
(Canadian Society for Pharmaceutical Sciences, 2017)PURPOSE: Liposomes have been studied as a colloidal carrier in drug delivery systems, especially for oral administration. However, their low structural integrity in the gut is still a major shortcoming. Membrane disruptive ... -
Nanostructured lipid carriers based suppository for enhanced rectal absorption of ondansetron: In vitro and in vivo evaluations
(Elsevier B.V., 2021)The current research aimed to fabricate ondansetron nanostructured lipid carriers (OND-NLCs) and incorporate them into a suppository base to manage chemotherapy-induced vomiting and nausea, which offer the advantage of ... -
Nanotechnology-Based Drug Delivery Approaches of Mangiferin: Promises, Reality and Challenges in Cancer Chemotherapy
(Multidisciplinary Digital Publishing Institute (MDPI), 2023)Mangiferin (MGF), a xanthone derived from Mangifera indica L., initially employed as a nutraceutical, is now being explored extensively for its anticancer potential. Scientists across the globe have explored this bioactive ... -
A narrative review of approved and emerging anti-obesity medications
(Elsevier B.V., 2023)Background: Recently, many drugs have been approved for halting overweight and obesity—few types of research shifted to using Anti-obesity medications (AOM) solely for well-being and shape-keeping. Objective: This narrative ... -
Natural resources governance and conflicts: Retrospective analysis
(Elsevier Ltd, 2023)Rapid increases in natural resources globally during the 1970s have had far-reaching environmental consequences. The rising exploitation of environmental assets has progressively detrimental societal effects. Therefore, ... -
Navigating the Complex Landscape of IoT Forensics: Challenges and Emerging Solutions
(Zarka Private University, 2023)With the increasing proliferation of the Internet of Things (IoT) devices, digital forensics professionals face numerous challenges while investigating cybercrimes. The vast number of IoT devices, the heterogeneity of their ... -
A nested square-shape dielectric resonator for microwave band antenna applications
(Institute of Advanced Engineering and Science, 2021)In this paper, a nested square-shape dielectric resonator (NSDR) has been designed and investigated for antenna applications in the microwave band. A solid square dielectric resonator (SSDR) was modified systematically by ... -
Neuroprotective effects of thymol, a dietary monoterpene against dopaminergic neurodegeneration in rotenone-induced rat model of parkinson’s disease
(MDPI AG., 2019)Parkinson’s disease (PD), a multifactorial movement disorder that involves progressive degeneration of the nigrostriatal system affecting the movement ability of the patient. Oxidative stress and neuroinflammation both are ... -
New algorithm for the approximate solution of generalized seventh order Korteweg-Devries equation arising in shallow water waves
(Elsevier B.V., 2021)In the present article, we present for the first time optimal auxiliary function method (OAFM) for partial differential equation (PDEs). To find efficient and precision the proposed method, we take Lax's seventh order ... -
A New ANN Technique for Short-Term Wind Speed Prediction Based on SCADA System Data in Turkey
(Multidisciplinary Digital Publishing Institute (MDPI), 2023-10)The restored interest now receives renewable energy due to the global decline in greenhouse gas emanations and fossil fuel combustion. The fasted growing energy source, wind energy generation, is recognized as a clean ... -
New approach for predicting the load-displacement curve of axially loaded piles in sand
(Elsevier Ltd, 2022)A relationship to predict the load-displacement curve for axially loaded piles in sandy soil is presented by using the tri-linear softening model to describe the shaft load-displacement relationships, as well as a bi-linear ... -
A new approach to fractional differential equations
(Serbian Society of Heat Transfer Engineers, 2023)In this work, we define fractional derivative of order ς > 0, with no restrictions on the domain of the function, and give its geometry. We derive some rules and properties for the proposed new approach and show that if ... -
A new fractional model for vector-host disease with saturated treatment function via singular and non-singular operators
(Elsevier B.V., 2021)In this paper, we consider a vector-host epidemic model with saturated incidence and treatment functions. This type of function is biologically more suitable in situations where the number of infected individuals is getting ... -
A New Hybrid Forecasting Model Based on Dual Series Decomposition with Long-Term Short-Term Memory
(Wiley-Hindawi, 2023)In recent years, ozone (O3) has gradually become the primary pollutant plaguing urban air quality. Accurate and efficient ozone prediction is of great significance to the prevention and control of ozone pollution. The air ... -
New Insights Into the Anticonvulsant Effects of Essential Oil From Melissa officinalis L. (Lemon Balm)
(Frontiers Media S.A., 2021)Melissa officinalis L. is used in traditional European and Iranian folk medicines to treat a plethora of neurological diseases including epilepsy. We utilized the in vitro and in vivo models of epilepsy to probe the ... -
A New Intrusion Detection System for the Internet of Things via Deep Convolutional Neural Network and Feature Engineering
(MDPI, 2022)The Internet of Things (IoT) is a widely used technology in automated network systems across the world. The impact of the IoT on different industries has occurred in recent years. Many IoT nodes collect, store, and process ...